Fig. 4

WT1-AS downregulated UCA1 to inhibit NSCLC cell invasion and migration. H1993 and H1581 cells were transfected with WT1-AS and UCA1 expression vectors and expression levels of UCA1 (left panel) and WT1-AS (right panel) were significantly increased at 24 h post-transfection comparing to NC and C groups (a). Compared to two controls (left panel), cells with UCA1 overexpression showed no significantly altered expression of WT1-AS, while WT1-AS overexpression led to inhibited UCA1 expression. And when WT1-AS was silenced, the expression of UCA1 was increased (right panel, b). NC, cells transfected with empty vector; C, untransfected cells. *, p < 0.05