Characteristics | SOX arm n=53 (%) | mFOLFOX6 arm n=50 (%) | p-value |
---|---|---|---|
Age (years) | |||
Median (range) | 63 (37–79) | 64 (36–79) | 0.3440 |
Sex | |||
Male | 44 (83.0) | 40 (80.0) | 0.6930 |
Female | 9 (17.0) | 10 (20.0) | |
Performance status (ECOG) | |||
0 | 53 (100.0) | 48 (96.0) | 0.2332 |
1 | 0 (0.0) | 2 (4.0) | |
Depth of wall invasion | |||
T3 | 39 (73.6) | 37 (74.0) | 0.9618 |
T4 | 14 (26.4) | 13 (26.0) | |
Lymph node metastasis | |||
N0 | 20 (37.7) | 16 (32.0) | 0.6317 |
N1 | 20 (37.7) | 20 (40.0) | |
N2 | 13 (24.5) | 12 (24.0) | |
N3a | 0 (0.0) | 2 (4.0) | |
RAS status | |||
Unexamined | 37 (70.0) | 36 (72.0) | 0.5945 |
Wild | 8 (15.1) | 11 (22.0) | |
Mutant | 8 (15.1) | 3 (6.0) | |
Past illness/comorbidity | |||
Yes | 23 (43.4) | 23 (46.0) | 1.0000 |
Cerebral infarction | 2 (3.8) | 3 (6.0) | |
Myocardial infarction | 1 (1.9) | 0 (0.0) | |
Hypertension | 15 (28.3) | 14 (28.0) | |
Diabetes | 8 (15.1) | 8 (16.0) | |
Others | 11 (20.8) | 11 (22.0) |