Table 3 Factors that contributed to non-e-curative outcome in patients with early gastric cancers after ESD
Clinico-pathologic parameters | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | |
Age (in years) | 1.05 (1.00–1.09) | 0.049 | 1.08 (1.01–1.17) | 0.029 |
Tumor location | ||||
 Lower one third | 1 (Reference) |  | 1 (Reference) |  |
 Middle or Upper third | 4.55 (2.04–10.12) | <  0.001 | 5.46 (1.65–18.12) | 0.006 |
Gross tumor type | ||||
  Group 1 | 1 (Reference) |  | 1 (Reference) |  |
  Group 2 | 5.70 (1.65–19.65) | 0.006 | 9.77 (1.23–77.65) | 0.031 |
Ulceration status | ||||
  Absent | 1 (Reference) |  |  1 (Reference) |  |
  Present | 3.03 (1.25–7.31) | 0.014 | 2.39 (0.59–9.65) | 0.223 |
Size of tumor | ||||
 ≤ 2 cm | 1 (Reference) |  |  1 (Reference) |  |
 >  2 cm | 6.19 (2.79–13.77) | <  0.001 | 7.63 (2.29–25.42) | 0.001 |
Differentiation | ||||
 Differentiated | 1 (Reference) |  | 1 (Reference) |  |
 Undifferentiated | 16.43 (6.60–40.89) | <  0.001 | 15.54 (1.65–146.22) | 0.016 |
Lauren’s category | ||||
 Intestinal | 1 (Reference) |  | 1 (Reference) |  |
 Non-intestinal | 16.43 (6.60–40.89) | <  0.001 | 3.29 (0.36–31.40) | 0.300 |