Fig. 2

Chondrogenic differentiation of mesenchymal stromal cells (MSCs) in the presence of R-2HG. a. Representative photos of pellet formation of MSCs after chondrogenic induction in the absence or presence of R-2HG (1, 1.5 mM). b. Collagen 2a staining for pellets in the absence or presence of R-2HG (1 mM). Scale bar = 20 μM (c): Quantitative results of expression levels of differentiation-related genes. * P < 0.05 vs the group of MSC in absence of R-2HG. ** P < 0.01 vs the group of MSC in absence of R-2HG