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Table 3 Univariate and multivariate analyses of predictive factors for survival of ovarian cancer patients

From: Mucinous, endometrioid, and serous ovarian cancers with peritoneal dissemination are potent candidates for P-cadherin targeted therapy: a retrospective cohort study

Factors

n

Disease-free survival

Overall survival

Univariate

P-value

Multivariate

Univariate

P-value

Multivariate

HR

95%CI

P-value

HR

95%CI

P-value

Age a (years)

 

.187

   

.176

   

  ≤ 55

79

        

  > 55

83

        

CA125a

 

6.3e-4*

2.29

1.08–4.84

.030*

.0017*

2.31

1.10–4.84

.027*

  ≤136

79

        

  > 136

81

        

Stageb (FIGO2014)

1.0e-7*

3.40

1.32–8.80

.011*

4.9e-7*

4.03

1.53–10.6

.0048*

  Stage I/II

88

        

  Stage III/IV

74

        

Peritoneal dissemination

5.0e-8*

4.06

1.42–11.6

.0090*

2.5e-6*

2.94

1.03–8.38

.044*

  Positive

76

        

  Negative

86

        

Lymph node metastasis

.091

   

.109

   

  Positive

24

        

  Negative

138

        

Distant site metastasis

.062

   

.095

   

  Positive

10

        

  Negative

152

        

Histologic typeb

 

.014*

0.42

0.20–0.92

.029*

.030*

0.42

0.19–0.93

.032*

  Serous

75

        

  Others

87

        

P-cadherin

 

.058

1.18

0.56–2.49

.669

.050

1.19

0.55–2.58

.653

  High

95

        

  Low

67

        
  1. Univariate and multivariate analyses of predictive factors for survival in ovarian cancer patients
  2. *P < 0.05. aCutoff value as the median value. bPathological diagnosis. CI confidence interval; HR hazard ratio
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