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Table 2 Factors associated with the prevalence of diagnosis

From: Thyroid cancer overdiagnosis and overtreatment: a cross- sectional study at a thyroid cancer referral center in Ecuador

  Incidental Univariate analysis Multivariate analysis  
Variables No Yes PR (95% CI) p   
  n = 206 n = 246     
Age, mean (SD) 43.0 (16.1) 46.3 (13.4) 1.01 (1.00,1.01) 0.037 1.01 (1.00, 1.02) 0.033
Sex, n (%)
 Male 14 (6.8) 12 (4.9) Reference 0.433   
 Female 192 (93.2) 234 (95.1) 1.19 (0.78, 1.81)   
Positive Family history n (%)
 No 179 (86.5) 211 (86.1) Reference 0.914   
 Yes 28 (13.6) 34 (13.8) 1.01 (0.79, 1.29)   
BMI, (n = 299) mean, (SD) n = 142
28.6 (5.7)
n = 157
29.2 (5.8)
1.00 (0.99, 1.02) 0.630   
Tumor size in mm, (n = 406) mean, (SD) n = 177
35.7 (17.9)
n = 229
22.3 (12.3)
0.96 (0.95, 0.97) 0.000 0.96 (0.94, 0.97) 0.000
Multifocal (n = 328), n (%)
 Unifocal, n (%) 103 (55.4) 127 (55.2) Reference 0.974 Reference 0.000
 Multifocal, n (%) 83 (44.6) 103 (44.8) 1.00 (0.84, 1.19) 1.32 (1.13, 1.54)
Positive Cervical Lymph nodes, n (%)
 No 93 (46.3) 132 (56.2) Reference 0.041 Reference 0.305
 Yes 108 (53.7) 103 (43.8) 0.83 (0.70, 0.99) 1.09 (0.93, 1.27)
MACIS score (n = 406), mean (SD) 5.6 (1.6) 4.9 (1.4) 0.86 (0.79, 0.92) 0.000 0.92 (0.81, 1.04) 0.184
Risk recurrence (n = 437)
 Very low risk 0 79 (33) Referencea    
 Low risk 147 (73.5) 124 (52.3)    
 Intermediate risk 33 (16.5) 16 (6.8) 0.56 (0.37, 0.85) 0.006 0.98 (0.67, 1.43) 0.902
 High risk 20 (10.0) 18 (7.6) 0.77 (0.54, 1.11) 0.163 1.04 (0.82, 2.16) 0.239
  1. a For univariate and multivariate analysis low and very low risk categories were combined and taken as reference