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Table 2 Factors associated with the prevalence of diagnosis

From: Thyroid cancer overdiagnosis and overtreatment: a cross- sectional study at a thyroid cancer referral center in Ecuador

 

Incidental

Univariate analysis

Multivariate analysis

 

Variables

No

Yes

PR (95% CI)

p

  
 

n = 206

n = 246

    

Age, mean (SD)

43.0 (16.1)

46.3 (13.4)

1.01 (1.00,1.01)

0.037

1.01 (1.00, 1.02)

0.033

Sex, n (%)

 Male

14 (6.8)

12 (4.9)

Reference

0.433

  

 Female

192 (93.2)

234 (95.1)

1.19 (0.78, 1.81)

  

Positive Family history n (%)

 No

179 (86.5)

211 (86.1)

Reference

0.914

  

 Yes

28 (13.6)

34 (13.8)

1.01 (0.79, 1.29)

  

BMI, (n = 299) mean, (SD)

n = 142

28.6 (5.7)

n = 157

29.2 (5.8)

1.00 (0.99, 1.02)

0.630

  

Tumor size in mm, (n = 406) mean, (SD)

n = 177

35.7 (17.9)

n = 229

22.3 (12.3)

0.96 (0.95, 0.97)

0.000

0.96 (0.94, 0.97)

0.000

Multifocal (n = 328), n (%)

 Unifocal, n (%)

103 (55.4)

127 (55.2)

Reference

0.974

Reference

0.000

 Multifocal, n (%)

83 (44.6)

103 (44.8)

1.00 (0.84, 1.19)

1.32 (1.13, 1.54)

Positive Cervical Lymph nodes, n (%)

 No

93 (46.3)

132 (56.2)

Reference

0.041

Reference

0.305

 Yes

108 (53.7)

103 (43.8)

0.83 (0.70, 0.99)

1.09 (0.93, 1.27)

MACIS score (n = 406), mean (SD)

5.6 (1.6)

4.9 (1.4)

0.86 (0.79, 0.92)

0.000

0.92 (0.81, 1.04)

0.184

Risk recurrence (n = 437)

 Very low risk

0

79 (33)

Referencea

   

 Low risk

147 (73.5)

124 (52.3)

   

 Intermediate risk

33 (16.5)

16 (6.8)

0.56 (0.37, 0.85)

0.006

0.98 (0.67, 1.43)

0.902

 High risk

20 (10.0)

18 (7.6)

0.77 (0.54, 1.11)

0.163

1.04 (0.82, 2.16)

0.239

  1. a For univariate and multivariate analysis low and very low risk categories were combined and taken as reference