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Table 2 Maximal treatment response

From: Survival benefit of ixazomib, lenalidomide and dexamethasone (IRD) over lenalidomide and dexamethasone (Rd) in relapsed and refractory multiple myeloma patients in routine clinical practice

 

IRD (N = 127)

RD (N = 217)

p1

Maximal treatment response, n (%)

n = 126

n = 216

 

sCR

2 (1.6%)

–

0.095

CR

12 (9.5%)

19 (8.8%)

VGPR

28 (22.2%)

30 (13.9%)

PR

50 (39.7%)

94 (43.5%)

MR

11 (8.7%)

34 (15.7%)

SD

13 (10.3%)

17 (7.9%)

PD

10 (7.9%)

22 (10.2%)

VGPR+ a

42 (33.3%)

49 (22.7%)

0.042

ORRb

92 (73.0%)

143 (66.2%)

0.227

CBRc

103 (81.7%)

177 (81.9%)

1.000

  1. a VGPR+ − patients reaching at least very good partial response
  2. b ORR – Overall Response Rate (PR or better)
  3. c CBR – Clinical Benefit Rate (MR or better)
  4. 1 p-value of Fisher’s exact test