| Univariate | Multivariate | ||
---|---|---|---|---|
HR (95% CI) | p | HR (95% CI) | p | |
Location | ||||
 Right (Ref.) |  | 0.039 |  | 0.020 |
 Left | 0.709 (0.400–1.256) | 0.238 | 0.659 (0.366–1.185) | 0.163 |
 Bilateral | 2.151 (0.943–4.907) | 0.069 | 2.331 (0.989–5.490) | 0.053 |
Histopathology | ||||
 Invasive cancer (Ref.) |  | 0.939 |  | 0.921 |
 DCIS | 0.894 (0.444–1.801) | 0.754 | 1.188 (0.508–2.780) | 0.691 |
 Other | 0.866 (0.203–3.698) | 0.846 | 1.079 (0.241–4.842) | 0.921 |
LVI | ||||
 Yes | 2.499 (1.469–4.250) | 0.001 | 1.709 (0.946–3.085) | 0.076 |
 No (Ref.) |  |  |  |  |
Pathologic N | ||||
 N0 (Ref.) |  | < 0.001 |  | < 0.001 |
 N1 | 2.598 (1.417–4.766) | 0.002 | 2.203 (1.163–4.172) | 0.015 |
 N2 | 7.758 (3.379–17.808) | < 0.001 | 6.823 (2.845–16.361) | < 0.001 |
 N3 | 8.752 (2.677–28.612) | < 0.001 | 6.331 (1.831–21.886) | 0.004 |
Pathologic prognostic stage | ||||
 0 & NRT (Ref.) |  | 0.025 |  | 0.179 |
 I | 1.443 (0.640–3.255) | 0.377 | 1.232 (0.461–3.288) | 0.677 |
 II | 1.221 (0.513–2.905) | 0.652 | 0.054 (0.170–1.713) | 0.295 |
 III | 3.769 (1.428–9.947) | 0.007 | 0.564 (0.145–2.200) | 0.410 |
Axillary op | ||||
 SLNB (Ref.) |  |  |  |  |
 ALND | 3.144 (1.826–5.414) | < 0.001 | 1.450 (0.674–3.123) | 0.342 |
PMRT + | ||||
 Yes | 2.731 (1.564–4.769) | < 0.001 | 1.101 (0.468–2.589) | 0.825 |
 No (Ref.) |  |  |  |  |
CTx. | ||||
 No (Ref.) |  | 0.067 |  | 0.775 |
 NAC | 1.681 (0.564–5.015) | 0.351 | 0.625 (0.168–2.328) | 0.483 |
 Adjuvant CTx. | 1.904 (1.101–3.295) | 0.021 | 0.839 (0.384–1.833) | 0.660 |