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Table 5 Univariate and multivariate analysis of risk factors for postoperative complication

From: Does chemotherapy or radiotherapy affect the postoperative complication in breast cancer patients who underwent immediate breast reconstruction with tissue expander?

 

Univariate

Multivariate

HR (95% CI)

p

HR (95% CI)

p

Location

 Right (Ref.)

 

0.039

 

0.020

 Left

0.709 (0.400–1.256)

0.238

0.659 (0.366–1.185)

0.163

 Bilateral

2.151 (0.943–4.907)

0.069

2.331 (0.989–5.490)

0.053

Histopathology

 Invasive cancer (Ref.)

 

0.939

 

0.921

 DCIS

0.894 (0.444–1.801)

0.754

1.188 (0.508–2.780)

0.691

 Other

0.866 (0.203–3.698)

0.846

1.079 (0.241–4.842)

0.921

LVI

 Yes

2.499 (1.469–4.250)

0.001

1.709 (0.946–3.085)

0.076

 No (Ref.)

    

Pathologic N

 N0 (Ref.)

 

< 0.001

 

< 0.001

 N1

2.598 (1.417–4.766)

0.002

2.203 (1.163–4.172)

0.015

 N2

7.758 (3.379–17.808)

< 0.001

6.823 (2.845–16.361)

< 0.001

 N3

8.752 (2.677–28.612)

< 0.001

6.331 (1.831–21.886)

0.004

Pathologic prognostic stage

 0 & NRT (Ref.)

 

0.025

 

0.179

 I

1.443 (0.640–3.255)

0.377

1.232 (0.461–3.288)

0.677

 II

1.221 (0.513–2.905)

0.652

0.054 (0.170–1.713)

0.295

 III

3.769 (1.428–9.947)

0.007

0.564 (0.145–2.200)

0.410

Axillary op

 SLNB (Ref.)

    

 ALND

3.144 (1.826–5.414)

< 0.001

1.450 (0.674–3.123)

0.342

PMRT +

 Yes

2.731 (1.564–4.769)

< 0.001

1.101 (0.468–2.589)

0.825

 No (Ref.)

    

CTx.

 No (Ref.)

 

0.067

 

0.775

 NAC

1.681 (0.564–5.015)

0.351

0.625 (0.168–2.328)

0.483

 Adjuvant CTx.

1.904 (1.101–3.295)

0.021

0.839 (0.384–1.833)

0.660

  1. DCIS Ductal carcinoma in situ, LVI Lymphovasvular invasion, NRT No residual tumor, SLNB Sentinel lymph node biopsy, ALND Axillary lymph node dissection, PMRT Post-mastectomy radiotherapy, NAC Neoadjuvant chemotherapy