Fig. 2From: Mesothelin blockage by Amatuximab suppresses cell invasiveness, enhances gemcitabine sensitivity and regulates cancer cell stemness in mesothelin-positive pancreatic cancer cellsEffect of Amatuximab on pancreatic cancer cell proliferation, invasion and migration. a AsPC-1, Capan-2, Panc-1 and MIA Paca-2 cells were incubated with the indicated concentrations of Amatuximab for 48 h. Viable cells were stained with trypan blue and counted. N.S., not significant. b, c Invasion assays were performed in AsPC-1, Capan-2, Panc-1 and MIA Paca-2 cells treated with Amatuximab (100 μg/mL) or control IgG (100 μg/mL) for 13 h. d, e Migration assays were performed in AsPC-1 cells and MIA Paca-2 cells treated with Amatuximab (100 μg/mL) or control IgG (100 μg/mL) for 13 h. *P < 0.05. 1HPF: one high power field. Scale bar, 100 μmBack to article page