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Table 2 Univariate Fine-Gray’s competing risk model analysis for CCD and KCD in patients with first primary kidney cancer

From: Competing risk analysis of cardiovascular/cerebrovascular death in T1/2 kidney cancer: a SEER database analysis

CCD

KCD

Characteristics

HR

95% CI for HR

p-value

HR

95% CI for HR

p-value

Age at diagnosis

 1–50

reference

  

reference

  

 51–58

2.131

1.760–2.560

< 0.001

1.650

1.440–1.890

< 0.001

 59–65

3.180

2.651–3.809

< 0.001

1.944

1.693–2.217

< 0.001

 66–73

4.973

4.182–5.908

< 0.001

2.240

1.966–2.563

< 0.001

 over 74

10.713

9.079–12.641

< 0.001

4.071

3.594–4.621

< 0.001

Marital status

 Sinlge/divorce/widow

reference

  

reference

  

 Marry

0.608

0.566–0.652

< 0.001

0.771

0.719–0.827

< 0.001

Race

 White

reference

  

reference

  

 Asian/Pacific Islander

0.781

0.646–0.943

0.010

1.058

0.903–1.240

0.490

 Black

1.366

1.238–1.507

< 0.001

0.922

0.825–1.030

0.150

 American Indian/Alaska Native

0.775

0.495–1.214

0.270

1.036

0.708–1.511

0.860

Sex

 Female

reference

  

reference

  

 Male

1.070

0.992–1.15

0.082

1.113

1.030–1.191

0.005

T (AJCC 6th)

 1

reference

  

reference

  

 2

0.882

0.796–0.978

0.017

3.483

3.244–3.746

< 0.001

N (AJCC 6th)

 0

reference

  

reference

  

 1

0.954

0.616–1.48

0.830

9.821

8.237–11.703

< 0.001

 2

0.369

0.118–1.15

0.086

14.498

11.151–18.808

< 0.001

Tumour size

  ≤ 3 cm

reference

  

reference

  

 >3 cm

1.160

1.083–1.247

< 0.001

3.462

3.140–3.814

< 0.001

Chemotherapy

 No

reference

  

reference

  

 Yes

0.604

0.369–0.987

0.044

8.062

6.891–9.433

< 0.001

Radiation therapy

 No

reference

  

reference

  

 Yes

1.833

1.200–2.781

0.004

8.260

6.672–10.207

< 0.001

Scope lymph node

 None

reference

  

reference

  

 1–3 regional lymph nodes removed

0.838

0.704–0.999

0.048

2.122

1.892–2.388

< 0.001

 4 or more regional lymph nodes removed

0.579

0.433–0.774

< 0.001

2.168

1.849–2.555

< 0.001

Surgey of primary site

 No operation

reference

  

reference

  

 Local tumour destruction/excision

0.134

0.107–0.166

< 0.001

0.179

0.145–0.221

< 0.001

partly nephrectomy

0.159

0.144–0.176

< 0.001

0.143

0.128–0.161

< 0.001

Radical nephrectomy

0.461

0.425–0.499

< 0.001

0.329

0.300–0.362

< 0.001

  1. Abbreviations: CCD cardiovascular and cerebrovascular death, KCD kidney cancer death, HR hazard ratio, CI confidence interval, AJCC American Joint Committee on Cancer
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BMC Cancer

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