Skip to main content

Table 2 Univariate Fine-Gray’s competing risk model analysis for CCD and KCD in patients with first primary kidney cancer

From: Competing risk analysis of cardiovascular/cerebrovascular death in T1/2 kidney cancer: a SEER database analysis

CCD KCD
Characteristics HR 95% CI for HR p-value HR 95% CI for HR p-value
Age at diagnosis
 1–50 reference    reference   
 51–58 2.131 1.760–2.560 < 0.001 1.650 1.440–1.890 < 0.001
 59–65 3.180 2.651–3.809 < 0.001 1.944 1.693–2.217 < 0.001
 66–73 4.973 4.182–5.908 < 0.001 2.240 1.966–2.563 < 0.001
 over 74 10.713 9.079–12.641 < 0.001 4.071 3.594–4.621 < 0.001
Marital status
 Sinlge/divorce/widow reference    reference   
 Marry 0.608 0.566–0.652 < 0.001 0.771 0.719–0.827 < 0.001
Race
 White reference    reference   
 Asian/Pacific Islander 0.781 0.646–0.943 0.010 1.058 0.903–1.240 0.490
 Black 1.366 1.238–1.507 < 0.001 0.922 0.825–1.030 0.150
 American Indian/Alaska Native 0.775 0.495–1.214 0.270 1.036 0.708–1.511 0.860
Sex
 Female reference    reference   
 Male 1.070 0.992–1.15 0.082 1.113 1.030–1.191 0.005
T (AJCC 6th)
 1 reference    reference   
 2 0.882 0.796–0.978 0.017 3.483 3.244–3.746 < 0.001
N (AJCC 6th)
 0 reference    reference   
 1 0.954 0.616–1.48 0.830 9.821 8.237–11.703 < 0.001
 2 0.369 0.118–1.15 0.086 14.498 11.151–18.808 < 0.001
Tumour size
  ≤ 3 cm reference    reference   
 >3 cm 1.160 1.083–1.247 < 0.001 3.462 3.140–3.814 < 0.001
Chemotherapy
 No reference    reference   
 Yes 0.604 0.369–0.987 0.044 8.062 6.891–9.433 < 0.001
Radiation therapy
 No reference    reference   
 Yes 1.833 1.200–2.781 0.004 8.260 6.672–10.207 < 0.001
Scope lymph node
 None reference    reference   
 1–3 regional lymph nodes removed 0.838 0.704–0.999 0.048 2.122 1.892–2.388 < 0.001
 4 or more regional lymph nodes removed 0.579 0.433–0.774 < 0.001 2.168 1.849–2.555 < 0.001
Surgey of primary site
 No operation reference    reference   
 Local tumour destruction/excision 0.134 0.107–0.166 < 0.001 0.179 0.145–0.221 < 0.001
partly nephrectomy 0.159 0.144–0.176 < 0.001 0.143 0.128–0.161 < 0.001
Radical nephrectomy 0.461 0.425–0.499 < 0.001 0.329 0.300–0.362 < 0.001
  1. Abbreviations: CCD cardiovascular and cerebrovascular death, KCD kidney cancer death, HR hazard ratio, CI confidence interval, AJCC American Joint Committee on Cancer
\