Skip to main content
Fig. 5 | BMC Cancer

Fig. 5

From: Intratumoral heterogeneity of second-harmonic generation scattering from tumor collagen and its effects on metastatic risk prediction

Fig. 5

F/B generated using histogram-based thresholding and its relation to MFS. SHG F/B values were produced using binary masks generated by a histogram-based thresholding method for each individual image taken in the a, tumor bulk and b, tumor-stroma interface. Patients were split into four equal quartiles (Q1 = lowest F/B) based on F/B, and the percentage of each quartile surviving without metastasis then plotted versus time. Tick marks represent censoring events caused when a patient dies of a cause other than cancer or is lost to follow-up. Partial likelihood ratio tests for ln F/B: p = 0.01 (tumor bulk, n = 95) and p = 0.0009 (tumor-stroma interface, n = 92)

Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us