Table 1 Multivariate analysis for Bcl-2 and miR-383 with clinicopathological parameters in GC patients
From: Translational control of Bcl-2 promotes apoptosis of gastric carcinoma cells
Parameter | Bcl-2-high | Bcl-2-low | P value | miR-383-high | miR-383-low | P value |
|---|---|---|---|---|---|---|
Age (years) | ||||||
< 60 | 12 (24%) | 11 (22%) | NS | 9 (18%) | 14 (28%) | NS |
> 60 | 13 (26%) | 14 (28%) | 16 (32%) | 11 (22%) | ||
Sex | ||||||
Male | 18 (36%) | 15 (30%) | NS | 14 (28%) | 19 (38%) | NS |
Female | 7 (14%) | 10 (20%) | 11 (22%) | 6 (12%) | ||
Lauren’s classification | ||||||
intestine | 17 (34%) | 22 (44%) | < 0.05 | 23 (46%) | 16 (32%) | < 0.05 |
diffuse | 8 (16%) | 3 (6%) | 2 (4%) | 9 (18%) | ||
TNM stage | ||||||
III + IV | 21 (42%) | 7 (14%) | < 0.05 | 9 (18%) | 20 (40%) | < 0.05 |
II | 4 (8%) | 18 (36%) | 16 (32%) | 5 (10%) | ||
Lymph node metastasis | ||||||
Present | 22 (44%) | 15 (30%) | < 0.05 | 15 (30%) | 22 (44%) | < 0.05 |
Absent | 3 (6%) | 10 (20%) | 10 (20%) | 3 (6%) | ||
Tumor location | ||||||
Upper 1/3 | 4 (8%) | 3 (6%) | NS | 3 (6%) | 4 (8%) | NS |
Middle 1/3 | 8 (16%) | 9 (18%) | 10 (20%) | 7 (14%) | ||
Lower 1/3 | 13 (26%) | 13 (26%) | 12 (24%) | 14 (28%) | ||