Fig. 4

Receiver operating characteristic (ROC) curve for ANXA1 antibodies in plasma from GBC cases and controls. (a) ROC curve analysis showed an Area under the ROC Curve (AUC) of 0.69 (95% CI: 0.52–0.86) with 41.7% sensitivity against a specificity of 89.9% in early stage GBC in comparison to controls and (b) an AUC of 0.73 (95% CI: 0.61–0.85) with 30.4% sensitivity against a specificity of 89.9% in lymph node negative GBC in comparison to controls