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Fig. 4 | BMC Cancer

Fig. 4

From: Inhibitory effects of iron depletion plus eribulin on the breast cancer microenvironment

Fig. 4

Expression levels of CA9 related gene in deferasirox-treated MDA-MB-231 and MCF-7 cells as measured by RT-PCR (a). Deferasirox upregulated CA9 expression in both MDA-MB-231 and MCF-7 cells, indicating that iron deficiency induces hypoxia. Expression levels of N-cadherin related gene in deferasirox-treated MDA-MB-231 and MCF-7 cells as measured by RT-PCR (b). Deferasirox treatment did not significantly change CDH2 expression levels in MDA-MB-231 and MCF-7 cells. Expression levels of PD-L1 related gene in deferasirox-treated MDA-MB-231 and MCF-7 cells as measured by RT-PCR (c). Deferasirox treatment did not change CD274 expression levels in MDA-MB-231 and MCF-7 cells

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