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Fig. 2 | BMC Cancer

Fig. 2

From: A novel TGF-β receptor II mutation (I227T/N236D) promotes aggressive phenotype of oral squamous cell carcinoma via enhanced EGFR signaling

Fig. 2

Effect of I227T/N236D TβRII mutation on xenograft tumor growth. a. Stable transfectant cells harboring an empty vector (IRES), wild-type TβRII (WT), or I227T/N236D TβRII (227/236) were orthotopically injected into the anterior tongue of mice. Tongue tumor sections were stained with H&E. Scale bar, 1 mm. b. Tongue tumor volume was measured at 4 weeks of injection. Data represent mean tumor volume ± standard deviation (* P < 0.05)

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