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Table 1 Baseline characteristics of the participants stratified by hs-CRP subgroups

From: A prospective follow-up study of the relationship between high-sensitivity C-reactive protein and primary liver cancer

 

hs-CRP

< 1 mg/L

1–3 mg/L

> 3 mg/L

F/X2

P- value

Number

52,867

24,522

18,370

  

Age (Year)

49.99 ± 12.08

52.40 ± 12.58

55.63 ± 12.48

1494.91

< 0.0001

Male (N)

42,603 (80.59)

19,602 (79.94)

14,335 (78.03)

55.28

< 0.0001

Sbp (mmHg)

129.08 ± 20.23

133.25 ± 21.54

134.27 ± 22.08

585.20

< 0.0001

Dbp (mmHg)

82.89 ± 11.55

84.54 ± 11.92

84.47 ± 12.10

225.80

< 0.0001

WC (cm)

85.29 ± 9.55

88.52 ± 9.73

90.14 ± 10.50

2046.10

< 0.0001

BMI (Kg/m2)

24.54 ± 3.31

25.76 ± 3.48

25.64 ± 3.76

1370.75

< 0.0001

TC (mmol/L)

4.90 ± 1.15

5.04 ± 1.15

4.96 ± 1.13

115.10

< 0.0001

TG (mmol/L)

1.21 (0.85 ~ 1.81)

1.38 (0.98 ~ 2.08)

1.35 (0.94 ~ 2.06)

1008.99

< 0.0001

FBG (mmol/L)

5.38 ± 1.49

5.60 ± 1.80

5.62 ± 1.99

203.33

< 0.0001

ALT (u/L)

18.12 (13.65 ~ 24.08)

19.63 (13.00 ~ 26.13)

18.09 (12.90 ~ 25.12)

252.39

< 0.0001

HDL-C (mmol/L)

1.56 ± 0.39

1.52 ± 0.39

1.58 ± 0.45

63.64

< 0.0001

LDL-C (mmol/L)

2.39 ± 0.78

2.45 ± 0.84

2.10 ± 1.26

877.22

< 0.0001

HBV infection + (N)

1519 (2.91)

671 (2.77)

426 (2.34)

16.43

0.0003

Hypertension (N)

20,741 (39.23)

11,850 (48.32)

9459 (51.49)

1092.35

< 0.0001

Diabetes (N)

3736 (7.07)

2710 (11.05)

2253 (12.26)

600.39

< 0.0001

Cirrhosis (N)

38 (0.07)

32 (0.13)

27 (0.15)

10.38

0.0056

NAFLD (N)

13,533 (25.67)

9559 (39.14)

7405 (40.42)

2139.65

< 0.0001

Family history of cancer (N)

1756 (3.32)

1045 (4.26)

624 (3.40)

45.05

< 0.0001

Smoking status (N)

16,613 (31.42)

7891 (32.18)

4617 (25.13)

303.65

< 0.0001

Drinking status (N)

9840 (18.61)

4519 (18.43)

2562 (13.95)

217.05

< 0.0001

Physical activity (N)

7746 (14.65)

4529 (18.47)

2471 (13.45)

253.56

< 0.0001

  1. SBP Systolic blood pressure, DBP Diastolic blood pressure, WC Waist circumference, BMI Body Mass Index, TC Total cholesterol, TG Triglycerides, FBG Fasting blood glucose, ALT Alanine aminotransferase, HDL-C High-density lipoprotein cholesterol, LDL-C Low-density lipoprotein cholesterol, HBV+ Hepatitis B virus infection, NAFLD Non-alcoholic fatty liver disease
  2. TG and ALT were skewed distributed variables and presented as median (interquartile range)