Table 2 Association between IL1RN expression and clinical parameters
Clinical parameters | L-IL1RN (n = 385, %) | H-IL1RN (n = 116, %) | P-value |
|---|---|---|---|
Age (y) | |||
  < 55 | 261 (67.8) | 73 (62.9) | 0.330 |
  ≥ 55 | 124 (32.2) | 43 (37.1) | |
Sex | |||
 Female | 282 (73.2) | 84(72.4) | 0.859 |
 Male | 103 (26.8) | 32(27.6) | |
Clinical stage | |||
 I | 224 (58.5) | 57 (49.1) | 0.001 |
 II | 47 (12.3) | 5 (4.3) | |
 III | 77 (20.1) | 34 (29.3) | |
 IV | 35 (9.1) | 20 (17.2) | |
 NA | 2 | 0 |  |
Metastasis | |||
 M0 | 208 (97.2) | 74 (96.1) | 0.635 |
 M1 | 6 (2.8) | 3 (3.9) | |
 NA | 171 | 39 |  |
N classification | |||
 N0 | 189 (54.8) | 40 (37.7) | 0.002 |
 N1 | 156 (45.2) | 66 (62.3) | |
 NA | 40 | 10 |  |
T classification | |||
 T1 | 120 (31.2) | 22 (19.3) | < 0.001 |
 T2 | 135 (35.1) | 29 (25.4) | |
 T3 | 116 (30.1) | 54 (47.4) | |
 T4 | 14 (3.6) | 9 (7.9) | |
 NA | 0 | 2 |  |
Pathologic type | |||
 Classical | 268 (69.6) | 87 (75.0) | < 0.001 |
 Follicular | 94 (24.4) | 7 (6.0) | |
 Tall Cell | 17 (4.4) | 19 (16.4) | |
 Other | 6 (1.6) | 3 (2.6) | |
BRAF | |||
 Wild | 179 (48.5) | 16 (14.3) | < 0.001 |
 Mutation | 190 (51.5) | 96 (85.7) | |
 NA | 16 | 4 |  |
RAS | |||
 Wild | 311 (84.3) | 110 (98.2) | < 0.001 |
 Mutation | 58 (15.7) | 2 (1.8) | |
 NA | 16 | 4 |  |