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Table 1 Sequential or concurrent dosing schedule in Rb WT and KD MCF-7 cells

From: Exploring treatment with Ribociclib alone or in sequence/combination with Everolimus in ER+HER2Rb wild-type and knock-down in breast cancer cell lines

A) Sequential dosing schedule
  3 days 2 days
1 Ribociclib Vehicle
2 Ribociclib Everolimus
3 Everolimus Vehicle
4 Everolimus Ribociclib
B) Concurrent dosing schedule
  3 days
1 Ribociclib + Everolimus
2 Ribociclib + Vehicle
3 Everolimus + Vehicle
  1. A) Sequential dosing schedule of combination of Rib and Eve; B) Concurrent dosing schedule of combination of Rib and Eve