Fig. 3

Effect of stimulation of B7-H6 on cell proliferation. Unsorted tumor cell lines were incubated with soluble recombinant NKp30 receptor. Proliferation was determined using the xCELLigence RTCA platform. In (a) HeLa, and (b) SiHa, the cells were stimulated with different concentrations of sNKp30 (5, 10, 20, 40, 60 and 80 ng/mL) and were compared with the basal (cells incubated only with media, 0 ng/mL NKp30). Cisplatin (1 μg/mL) was used as a control for the inhibition of proliferation. Proliferation was evaluated for 96 h. The graphs reflect the results of three independent experiments performed in sextuplicate; *p < 0.05 (analysis of variance)