Fig. 1

Localization of IFNL gene polymorphisms under study and calculation of LD. The 5 IFNL gene polymorphisms of interest are located within the 5′ and 3′ termini of the IFNL3 gene and within exon 1 and 2 and intron 1 of IFNL4 gene on chromosome 19 as shown. The normalized coefficients of LD (D’) and the correlation coefficients (r²) were calculated on data provided by the 1000 Genomes Project for individuals of European ancestry (n = 503). With the exception of IFNL4 rs117648444, they qualify as mutual tagSNPs