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Table 1 Demographics and clinical characteristics for the metastatic RCC patients

From: Development and validation of a nomogram to predict overall survival for patients with metastatic renal cell carcinoma

Variables All patients (n = 2315) Training set (n = 1158) Validation set (n = 1157)
No. (%) No. (%) No. (%)
Age (years) 61 (54–68) 60 (54–68) 61 (54–68)
Race
 White 1941 (83.8%) 968 (83.6%) 973 (84.1%)
 Black 174 (7.5%) 92 (7.9%) 82 (7.1%)
 Other 200 (8.6%) 98 (8.5%) 102 (8.8%)
Sex
 Male 1629 (70.4%) 812 (70.1%) 817 (70.6%)
 Female 686 (29.6%) 346 (29.9%) 340 (29.4%)
Marital status
 Married 1559 (67.3%) 777 (67.1%) 782 (67.6%)
 Unmarried 756 (32.7%) 381 (32.9%) 375 (32.4%)
Histologic subtype
 CCRCC 1959 (84.6%) 982 (84.8%) 977 (84.4%)
 PRCC 142 (6.1%) 56 (4.8%) 86 (7.4%)
 CHRCC 27 (1.2%) 14 (1.2%) 13 (1.1%)
 SRCC 168 (7.3%) 91 (7.9%) 77 (6.7%)
 CDRCC 19 (0.8%) 15 (1.3%) 4 (0.3%)
Fuhrman grade
 Grade I 57 (2.5%) 26 (2.2%) 31 (2.7%)
 Grade II 516 (22.3%) 247 (21.3%) 269 (23.2%)
 Grade III 926 (40.0%) 482 (41.6%) 444 (38.4%)
 Grade IV 816 (35.2%) 403 (34.8%) 413 (35.7%)
Tumor size (mm) 90 (70–118) 90.5 (70–120) 90 (68–115)
Tumor classification
 T1 289 (12.5%) 141 (12.2%) 148 (12.8%)
 T2 383 (16.5%) 198 (17.1%) 185 (16.0%)
 T3 1316 (56.8%) 661 (57.1%) 655 (56.6%)
 T4 293 (12.7%) 143 (12.3%) 150 (13.0%)
 TX 34 (1.5%) 15 (1.3%) 19 (1.6%)
Lymph node status
 N0 1618 (69.9%) 796 (68.7%) 822 (71.0%)
 N1 597 (25.8%) 310 (26.8%) 287 (24.8%)
 NX 100 (4.3%) 52 (4.5%) 48 (4.1%)
Sarcomatoid feature
 Yes 446 (19.3%) 220 (19.0%) 226 (19.5%)
 No 1697 (73.3%) 848 (73.2%) 849 (73.4%)
 Unknown 172 (7.4%) 90 (7.8%) 82 (7.1%)
Cancer-directed surgery
 Recommended and performed 1982 (85.6%) 980 (84.6%) 1002 (86.6%)
 Recommended but not performed 21 (0.9%) 12 (1.1%) 9 (0.6%)
 Not recommended 312 (13.5%) 166 (14.3%) 146 (12.8%)
Bone metastasis
 Yes 729 (31.5%) 361 (31.2%) 368 (31.8%)
 No 1586 (68.5%) 797 (68.8%) 789 (68.2%)
Brain metastasis
 Yes 230 (9.9%) 112 (9.7%) 118 (10.2%)
 No 2085 (90.1%) 1046 (90.3%) 1039 (89.8%)
Liver metastasis
 Yes 254 (11.0%) 126 (10.9%) 128 (11.1%)
 No 2061 (89.0%) 1032 (89.1%) 1029 (88.9%)
Lung metastasis
 Yes 1429 (61.7%) 723 (62.4%) 706 (61.0%)
 No 886 (38.3%) 435 (37.6%) 451 (39.0%)
  1. Abbreviation: CCRCC clear cell renal cell carcinoma, PRCC papillary renal cell carcinoma, CHRCC chromophobe renal cell carcinoma, SRCC sarcomatoid renal cell carcinoma, CDRCC collecting duct renal cell carcinoma
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