Risk Factor | Category | Description | Number | % | Number | % | Median | SD | Median | SD | OR | OR CI 95% | P-value |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Controls | Controls | Cases | Cases | Control | Control | Cases | Cases | ||||||
Age | 0 | 30–35 years | 28 | 4,36 | 16 | 3,52 | 51 | 8,18 | 51 | 8,14 | 1,05 | 0.79–1.13 | 0,27 |
1 | 35–40 years | 58 | 9,03 | 28 | 6,15 | ||||||||
2 | 40–45 years | 84 | 13,08 | 63 | 13,85 | ||||||||
3 | 45–50 years | 138 | 21,5 | 115 | 25,27 | ||||||||
4 | 50–55 years | 158 | 24,61 | 86 | 18,9 | ||||||||
5 | 55–60 years | 113 | 17,6 | 94 | 20,66 | ||||||||
6 | 60–65 years | 47 | 7,32 | 37 | 8,13 | ||||||||
7 | > 65 years | 16 | 2,49 | 16 | 3,52 | ||||||||
Breast Density | 0 | From 0 to 10% | 99 | 15,42 | 51 | 11,21 | 2 | 1,2 | 3 | 1,3 | 1,46 | 1.21–1.71 | 1,64E-07 |
1 | From 11 to 25% | 116 | 18,07 | 53 | 11,65 | ||||||||
2 | From 26 to 50% | 185 | 28,82 | 116 | 25,49 | ||||||||
3 | From 51 to 75% | 181 | 28,19 | 133 | 29,23 | ||||||||
4 | Greater than 75% | 61 | 9,5 | 102 | 22,42 | ||||||||
Age at first delivery | 0 | Less than 20 years | 33 | 5,14 | 23 | 5,05 | 2 | 1,4 | 2 | 1,46 | 1,15 | 1.02–1.31 | 0,03 |
1 | From 20 to 24 years | 165 | 25,7 | 104 | 22,86 | ||||||||
2 | From 25 to 29 years | 203 | 31,62 | 107 | 23,52 | ||||||||
3 | From 30 to 34 years | 106 | 16,51 | 101 | 22,2 | ||||||||
4 | Greater than 34 years | 56 | 8,72 | 50 | 10,99 | ||||||||
5 | Nulliparous | 79 | 12,31 | 70 | 15,38 | ||||||||
Age at menopause | 0 | Less than 46 years | 97 | 15,11 | 47 | 10,33 | 2 | 1,4 | 3 | 1,13 | 1,96 | 1.72–2.24 | 2,20E-16 |
1 | From 46 to 50 years | 147 | 22,9 | 102 | 22,42 | ||||||||
2 | Greater than 50 years | 110 | 17,13 | 71 | 15,6 | ||||||||
3 | Premenopause | 87 | 13,55 | 212 | 46,59 | ||||||||
4 | Menstruating | 201 | 31,31 | 23 | 4,97 | ||||||||
Age at menarche | 0 | Equal to or greater than 15 years | 34 | 5,3 | 34 | 7,47 | 2 | 1,21 | 3 | 1,2 | 0,89 | 0.78–1.04 | 0,061 |
1 | 14 years | 115 | 17,91 | 85 | 18,68 | ||||||||
2 | 13 years | 178 | 27,73 | 100 | 21,98 | ||||||||
3 | 12 years | 140 | 21,81 | 110 | 24,18 | ||||||||
4 | Less than 12 years | 175 | 27,26 | 123 | 27,03 | ||||||||
5 | Null | 0 | 0 | 3 | 0,66 | ||||||||
Family antecedents | 0 | No affected relative | 468 | 72,9 | 308 | 67,69 | 0 | 1,16 | 0 | 1,23 | 1,05 | 0.93–1.19 | 0,34 |
1 | A first-degree relative diagnosed with breast cancer at age 50 years or older | 52 | 8,1 | 43 | 9,45 | ||||||||
2 | A first-degree relative diagnosed with breast cancer when younger than 50 years | 25 | 3,89 | 18 | 3,96 | ||||||||
3 | 1 affected second-degree relative | 90 | 14,02 | 79 | 17,36 | ||||||||
4 | 2 affected first-degree relatives | 4 | 0,62 | 5 | 1,1 | ||||||||
5 | 2 affected second-degree relatives | 1 | 0,16 | 2 | 0,44 | ||||||||
6 | 3 or more affected relatives | 2 | 0,31 | 0 | 0 |