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Table 5 Spontaneous colorectal perforation. Logistic regression with spontaneous colorectal perforation at presentation as dependent variablea

From: Long-term trends in colorectal cancer: incidence, localization, and presentation

 

Perforations (%)

Unadjusted odds ratio

P value

Adjusted odds ratio

P value

Female sex

30/1074 (2.8)

0.87 (0.54–1.42)

0.59

0.81 (0.48–1.35)

0.42

Age

 

0.99 (0.97–1.005)

0.13

0.98 (0.96–1.01)

0.14

Year of diagnosis

 

0.96 (0.93–0.98)

< 0.001

0.97 (0.94–0.99)

0.009

T-Stage

  

< 0.001

 

< 0.001

 1–2

1/418 (0.2)

1

 

1

 

 3

27/1202 (2.2)

9.58 (1.30–71)

0.027

8.57 (1.16–64)

0.036

 4

38/437 (8.7)

39.7 (5.43–291)

< 0.001

36.7 (4.97–272)

< 0.001

 Unknown

0/89 (0)

0

0.997

0

0.997

Location

 Caecum

14/288 (4.9)

10.0 (1.31–77)

0.027

9.25 (1.18–73)

0.034

 Ascending colon

5/310 (1.6)

3.12 (0.37–28)

0.03

3.59 (0.41–31)

0.25

 Right flexure

3/99 (3.0)

6.13 (0.63–60)

0.12

5.17 (0.52–52)

0.16

 Transverse colon

2/158 (1.3)

2.51 (0.23–28)

0.45

2.38 (0.21–27)

0.49

 Left flexure

2/62 (3.2)

6.53 (0.58–73)

0.13

5,60 (0.49–64)

0.17

 Descending colon

5/93 (5.4)

11.14 (1.28–97)

0.029

13,7 (1.54–123)

0.019

 Sigmoid

26/541 (4.8)

9.90 (1.33–73)

0.025

11.9 (1.57–90)

0.017

 Proximal rectum

5/220 (2.3)

4.56 (0.53–39)

0.14

5.40 (0.61–48)

0.13

 Middle rectum

5/300 (1.7)

3.32 (0.39–29)

0.28

2.68 (0.29–25)

0.38

 Distal rectum

1/197 (0.5)

1

 

1

 
  1. a Sex, age, year of diagnosis, and location of the primary tumour as covariates. Unadjusted, and adjusted for age, sex, year of diagnosis, and T-stage. Distal rectal cancer was used as the reference location