From: Long-term trends in colorectal cancer: incidence, localization, and presentation
Perforations (%) | Unadjusted odds ratio | P value | Adjusted odds ratio | P value | |
---|---|---|---|---|---|
Female sex | 30/1074 (2.8) | 0.87 (0.54–1.42) | 0.59 | 0.81 (0.48–1.35) | 0.42 |
Age | 0.99 (0.97–1.005) | 0.13 | 0.98 (0.96–1.01) | 0.14 | |
Year of diagnosis | 0.96 (0.93–0.98) | < 0.001 | 0.97 (0.94–0.99) | 0.009 | |
T-Stage | < 0.001 | < 0.001 | |||
1–2 | 1/418 (0.2) | 1 | 1 | ||
3 | 27/1202 (2.2) | 9.58 (1.30–71) | 0.027 | 8.57 (1.16–64) | 0.036 |
4 | 38/437 (8.7) | 39.7 (5.43–291) | < 0.001 | 36.7 (4.97–272) | < 0.001 |
Unknown | 0/89 (0) | 0 | 0.997 | 0 | 0.997 |
Location | |||||
Caecum | 14/288 (4.9) | 10.0 (1.31–77) | 0.027 | 9.25 (1.18–73) | 0.034 |
Ascending colon | 5/310 (1.6) | 3.12 (0.37–28) | 0.03 | 3.59 (0.41–31) | 0.25 |
Right flexure | 3/99 (3.0) | 6.13 (0.63–60) | 0.12 | 5.17 (0.52–52) | 0.16 |
Transverse colon | 2/158 (1.3) | 2.51 (0.23–28) | 0.45 | 2.38 (0.21–27) | 0.49 |
Left flexure | 2/62 (3.2) | 6.53 (0.58–73) | 0.13 | 5,60 (0.49–64) | 0.17 |
Descending colon | 5/93 (5.4) | 11.14 (1.28–97) | 0.029 | 13,7 (1.54–123) | 0.019 |
Sigmoid | 26/541 (4.8) | 9.90 (1.33–73) | 0.025 | 11.9 (1.57–90) | 0.017 |
Proximal rectum | 5/220 (2.3) | 4.56 (0.53–39) | 0.14 | 5.40 (0.61–48) | 0.13 |
Middle rectum | 5/300 (1.7) | 3.32 (0.39–29) | 0.28 | 2.68 (0.29–25) | 0.38 |
Distal rectum | 1/197 (0.5) | 1 | 1 |