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Table 5 Spontaneous colorectal perforation. Logistic regression with spontaneous colorectal perforation at presentation as dependent variablea

From: Long-term trends in colorectal cancer: incidence, localization, and presentation

  Perforations (%) Unadjusted odds ratio P value Adjusted odds ratio P value
Female sex 30/1074 (2.8) 0.87 (0.54–1.42) 0.59 0.81 (0.48–1.35) 0.42
Age   0.99 (0.97–1.005) 0.13 0.98 (0.96–1.01) 0.14
Year of diagnosis   0.96 (0.93–0.98) < 0.001 0.97 (0.94–0.99) 0.009
T-Stage    < 0.001   < 0.001
 1–2 1/418 (0.2) 1   1  
 3 27/1202 (2.2) 9.58 (1.30–71) 0.027 8.57 (1.16–64) 0.036
 4 38/437 (8.7) 39.7 (5.43–291) < 0.001 36.7 (4.97–272) < 0.001
 Unknown 0/89 (0) 0 0.997 0 0.997
Location
 Caecum 14/288 (4.9) 10.0 (1.31–77) 0.027 9.25 (1.18–73) 0.034
 Ascending colon 5/310 (1.6) 3.12 (0.37–28) 0.03 3.59 (0.41–31) 0.25
 Right flexure 3/99 (3.0) 6.13 (0.63–60) 0.12 5.17 (0.52–52) 0.16
 Transverse colon 2/158 (1.3) 2.51 (0.23–28) 0.45 2.38 (0.21–27) 0.49
 Left flexure 2/62 (3.2) 6.53 (0.58–73) 0.13 5,60 (0.49–64) 0.17
 Descending colon 5/93 (5.4) 11.14 (1.28–97) 0.029 13,7 (1.54–123) 0.019
 Sigmoid 26/541 (4.8) 9.90 (1.33–73) 0.025 11.9 (1.57–90) 0.017
 Proximal rectum 5/220 (2.3) 4.56 (0.53–39) 0.14 5.40 (0.61–48) 0.13
 Middle rectum 5/300 (1.7) 3.32 (0.39–29) 0.28 2.68 (0.29–25) 0.38
 Distal rectum 1/197 (0.5) 1   1  
  1. a Sex, age, year of diagnosis, and location of the primary tumour as covariates. Unadjusted, and adjusted for age, sex, year of diagnosis, and T-stage. Distal rectal cancer was used as the reference location
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