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Table 2 Cohort split into EpCAM classification groups. Group differences assessed by Fisher’s Exact test for categorical variables and Kruskal-Wallis-test for numerical variables

From: Hepatocellular carcinoma: Intratumoral EpCAM-positive cancer stem cell heterogeneity identifies high-risk tumor subtype

Baseline Characteristics

EpCAM-negative n = 29 (42.1%)

EpCAM- heterogeneous n = 33 (47.8%)

EpCAM- homogeneous n = 7 (10.1%)

p-value

Sex

 m

24 (77.42)

26 (78.79)

5 (71.43)

0.920

 f

7 (22.58)

7 (21.21)

2 (28.57)

Age at surgical procedure (years)

 range

38–84

18–81

58–76

0.326

 median (n)

69 (29)

66 (33)

63 (7)

ECOG

 0

17 (58.62)

18 (56.25)

2 (33.33)

0.535

 1

11 (37.93)

14 (43.75)

4 (66.67)

 2

1 (3.45)

0 (0)

0 (0)

BCLC

 A

19 (70.37)

18 (64.29)

2 (33.33)

0.152

 B

8 (29.63)

7 (25)

3 (50)

 C

0 (0)

3 (10.71)

1 (16.67)

Histological Stage of Liver

 No Fibrosis

6 (22.22)

6 (21.43)

3 (42.86)

0.808

 Fibrosis

10 (37.04)

9 (32.14)

2 (28.57)

 Cirrhosis

11 (40.74)

13 (46.43)

2 (28.57)

Child Pugh Stage

 A

11 (100)

11 (84.62)

1 (50)

0.111

 B

0 (0)

2 (15.38)

1 (50)

Aetiology

 Alcohol

9 (24.32)

11 (29.73)

2 (20)

0.617

 HBV

7 (18.92)

4 (10.81)

2 (20)

 HCV

9 (24.32)

5 (13.51)

1 (10)

 NASH

4 (10.81)

7 (18.92)

0 (0)

 Other

4 (10.81)

3 (8.11)

2 (20)

 w/o liver disease

4 (10.81)

7 (18.92)

3 (30)

Bilirubin

 range

0.3–1.7

0.3–2.3

0.4–0.7

0.105

 median (n)

0.65 (22)

0.5 (25)

0.5 (7)

Albumin

 range

31–43

2.34–43

30–42

0.152

 median (n)

38 (20)

36 (21)

35 (6)

INR

 range

0.93–2.42

0.92–3.08

0.95–1.25

0.863

 median (n)

1.06 (25)

1.055 (24)

1.06 (6)