Clinical characteristics | Patient 5 | Patient 6 | Patient 7 | Patient 8 | Patient 9 | Patient 10 | Patient 11 |
---|---|---|---|---|---|---|---|
Residence | Hangzhou | Huzhou | Hangzhou | Heilongjiang | Hangzhou | Ningbo | Hangzhou |
Date of admission | 11-Feb 2020 | 18-Feb 2020 | 20-Feb 2020 | 25-Feb 2020 | 26-Feb 2020 | 10-Mar 2020 | 16-Mar 2020 |
Age (years) | 60 | 71 | 67 | 78 | 54 | 49 | 61 |
Gender | Female | Male | Male | Male | Male | Female | Male |
Cancer type | Breast cancer | Lung cancer | Oropharyngeal cancer | Lung cancer | Liver cancer | Colorectal cancer | Esophageal cancer |
Smoking status | No | Yes | Yes | No | Yes | No | Yes |
Epidemiological history | No | No | No | No | No | No | No |
Other diseases | Hypertension | Liver cancer | Parotid gland carcinoma | Colorectal cancer and liver cancer | No | Hypertension | Hypertension |
Treatment History | Surgery 2 weeks ago | Chemotherapy 1 week ago | Chemotherapy and immunotherapy 1 week ago | Newly diagnosed | Newly diagnosed | Newly diagnosed | Neoadjuvant chemotherapy 1 month ago |
Symptoms | |||||||
 Fever | No | No | No | Yes(38.3 °C) | Yes(39.7 °C) | No | No |
 Cough | No | Yes | Yes | Yes | No | No | Yes |
 Fatigue or myalgia | No | Yes | No | No | No | No | Yes |
 Expectoration | No | Yes | No | Yes | No | No | No |
 Dyspnea | No | Yes | No | No | No | No | No |
 Headache | No | No | No | No | No | No | Yes |
 Diarrhea | No | No | No | No | No | No | No |
 White blood cell count (× 109 cells per L) | 7.3 | 5.4 | 5.8 | 5.2 | 6.8 | 3.8 | 4.6 |
 Low leukocyte count (< 9.5 × 109 cells per L) | No | No | No | No | No | No | No |
 Lymphocyte count (× 109 cells per L) | 1.6 | 1.2 | 1.1 | 1.1 | 1.9 | 1.8 | 0.9 |
 Lymphopenia (< 109 cells per L) | No | No | No | No | No | No | Yes |
 CRP (mg/L) | 1.84 | 2.45 | 2.2 | 7.73 | 9.39 | 1.07 | 0.49 |
 Elevated CRP (> 10 mg/L) | No | No | No | No | No | No | No |
 LDH (U/L) | 226 | 289 | 256 | 139 | 188 | 160 | 184 |
 Elevated LDH (> 240 U/L) | No | Yes | Yes | No | No | No | No |
 ALT (U/L) | 63 | 17 | 58 | 8 | 15 | 15 | 12 |
 Elevated ALT (> 50 U/L) | Yes | No | Yes | No | No | No | No |
 AST (U/L) | 38 | 22 | 54 | 14 | 47 | 22 | 16 |
 Elevated AST (> 40 U/L) | No | No | Yes | No | Yes | No | No |
1st round of PCR | |||||||
 RNA-dependent RNA polymerase (RdRp) | Negative | Negative | Negative | Negative | Negative | Negative | Negative |
 Nucleocapsid (N) gene | Positive | Positive | Positive | Positive | Positive | Positive | Positive |
2nd round of PCR | |||||||
 RNA-dependent RNA polymerase (RdRp) | Negative | Negative | Negative | Negative | Negative | Negative | Negative |
 Nucleocapsid (N) gene | Positive | Positive | Positive | Negative | Negative | Positive | Positive |
CT evidence of pneumonia | |||||||
 Typical signs of viral infection | Positive | Negative | Negative | Negative | Negative | Negative | Negative |
Follow-up Treatment | |||||||
 | Transfer to a designated hospital | Chemotherapy | Transfer to a local hospital | Anti-infection therapy | Anti-infection therapy and chemotherapy | Laparoscopic radical resection | Chemotherapy |