|
Variable
|
SLFN-11 expression
|
P value
|
|---|
|
Low
|
High
|
|---|
|
n (%)
|
n (%)
|
|---|
|
Gender
|
Male
|
32 (52.5)
|
29 (47.5)
|
0.345
|
|
Female
|
4 (33.3)
|
8 (66.7)
|
|
Age
|
< 65
|
9 (34.6)
|
17 (65.4)
|
0.062
|
|
≥ 65
|
27 (57.4)
|
20 (42.6)
|
|
Number of pre-dCRT biopsy specimens including tumor tissue
|
1
|
5 (45.5)
|
6 (54.5)
|
0.781
|
|
≥ 2
|
31 (50.0)
|
31 (50.0)
|
|
Histological type
|
Differentiated
|
33 (51.6)
|
31 (48.4)
|
0.725
|
|
Un-differentiated
|
3 (33.3)
|
6 (66.7)
|
|
Depth of invasion
|
cT1b or T2
|
12 (50.0)
|
12 (50.0)
|
0.935
|
|
cT3 - T4b
|
24 (49.0)
|
25 (51.0)
|
|
Tumor size
|
< 5 cm
|
17 (48.6)
|
18 (51.4)
|
0.903
|
|
≥ 5 cm
|
19 (50.0)
|
19 (50.0)
|
|
Lymphatic metastasis
|
cN0
|
11 (45.8)
|
13 (54.2)
|
0.677
|
|
(regional lymph node)
|
cN1 - N3
|
25 (51.0)
|
24 (49.0)
|
|
Distant metastasis
|
cM0
|
32 (50.8)
|
31 (49.2)
|
0.736
|
|
(distant lymph node)
|
cM1 -lym
|
4 (40.0)
|
6 (60.0)
|
- Abbreviations: CI confidence interval, cT1b tumor invasion to the submucosa, cT2 tumor invasion to the muscularis propria, cT3 tumor invasion to the adventitia, cT4b tumor invades adjacent structures, such as the aorta, vertebral body, or trachea, cN0 no regional lymph node metastasis, cN1 metastasis in 1–2 regional lymph nodes, cN3 metastasis in 7 or more regional lymph nodes, cM0 no distant metastasis, cM1-lym distant lymph node metastasis, dCRT definitive chemoradiotherapy
