The value of haematological parameters and serum tumour markers for predicting KRAS mutations in 784 Chinese colorectal cancer patients: a retrospective analysis

Table 3 Shows ROC analysis, AUC (area under curve), standard error, condence interval and P values of hematological parameters and STMs

	AUC	Standard error	95%CI		P
	AUC	Standard error	Low bound	Upper bound	P
Age	0.531	0.021	0.489	0.572	0.154
CEA	0.574	0.022	0.531	0.617	0.001
CA125	0.529	0.021	0.487	0.571	0.177
CA199	0.579	0.021	0.537	0.620	< 0.001
AFP	0.524	0.023	0.480	0.569	0.277
SCC	0.524	0.026	0.473	0.575	0.350
NSE	0.546	0.023	0.501	0.590	0.043
CA72.4	0.504	0.022	0.460	0.548	0.864
CA15.3	0.502	0.025	0.452	0.552	0.941
FERR	0.549	0.026	0.497	0.600	0.066
CYFRA21-1	0.528	0.026	0.477	0.579	0.279
WBC	0.563	0.021	0.521	0.605	0.003
MON	0.606	0.021	0.565	0.648	< 0.001
MLR	0.571	0.021	0.531	0.612	0.001
Mon%	0.561	0.021	0.519	0.602	0.005
HCT	0.546	0.022	0.504	0.589	0.031
HGB	0.547	0.022	0.504	0.589	0.030
AVEMPV	0.557	0.024	0.511	0.604	0.016
MCH	0.552	0.021	0.510	0.594	0.015
MCHC	0.523	0.022	0.480	0.566	0.293
MCV	0.551	0.021	0.509	0.593	0.019
HDLC	0.563	0.023	0.519	0.607	0.006
Tumor location	0.542	0.022	0.499	0.585	0.053

CEA Carcinoembryonic antigen, CA 125 Carbohydrate antigen 125, CA 19–9 Carbohydrate antigen 19–9, SCC Squamous cell carcinoma antigen, NSE Neuronspecific enolase, CA 724 Carbohydrate antigen 72–4, FERR Ferritin, CYFRA21-1 Human cytokeratin fragment antigen 21–1, WBC White blood cell, MON Monocyte, MLR Monocyte /Lymphocyte, HCT Hematocrit, HGB Hemoglobin, AVEMPV Mean platelet volume, MCH Mean corpuscular hemoglobin, MCHC Mean corpusular hemoglobin concerntration, MCV Mean corpuscular volume, HDLC High-density lipoprotein

ISSN: 1471-2407