Table 2 Correlation between JMJD6 and EZH2 expression in breast normal and tumor samples before and after subclassification based on histopathological and molecular subtyping
From: Both EZH2 and JMJD6 regulate cell cycle genes in breast cancer
JMJD6-EZH2 | ||||
|---|---|---|---|---|
# Samples (n) | Pearson (r) | p-value | Spearman (rs) | p-value |
Normal (23) | 0.879 | 3.00E-08 | 0.935 | 7.00E-11 |
Tumor (63) | 0.91 | 6.00E-25 | 0.889 | 2.00E-22 |
Type | ||||
IDC3 (42) | 0.921 | 6.00E-18 | 0.829 | 1.00E-11 |
DCIS & IDC2(14) | 0.916 | 4.00E-06 | 0.943 | 2.00E-06 |
Subtypes | ||||
Non-TNBC (31) | 0.864 | 4.00E-10 | 0.811 | 3.00E-08 |
TNBC (25) | 0.965 | 8.00E-15 | 0.94 | 3.00E-12 |
ER+ (17) | 0.877 | 4.00E-06 | 0.877 | 1.00E-05 |
ER- (39) | 0.936 | 2.00E-18 | 0.858 | 3.00E-12 |
HER2+ (18) | 0.806 | 5.00E-05 | 0.711 | 0.001 |
HER2- (38) | 0.918 | 6.00E-16 | 0.92 | 4.00E-16 |