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Fig. 1 | BMC Cancer

Fig. 1

From: Increased E2F2 predicts poor prognosis in patients with HCC based on TCGA data

Fig. 1

E2F2 had a high expression in HCC. a E2F2 showed prominently high expression in HCC tissues than in normal tissues (p = 3.428e−25) based on Wilcoxon rank sum test. b The expression of E2F2 was significantly increased in HCC tissues compared with adjacent non-cancerous tissues based on Wilcoxon signed-rank test. c and d showed E2F2 was prominently overexpressed in HCC samples from GSE124535 and GSE54236. e and f validation of protein expression levels of hub genes in the HPA database. Original magnification was × 200 μm.((E) https://www.proteinatlas.org/ENSG00000007968-E2F2/tissue/liver#img; (F) https://www.proteinatlas.org/ENSG00000007968-E2F2/pathology/liver+cancer#img); g IOD level of hub genes in IHC sample images. **p < 0.01 compared with normal. IHC: immunohistochemistry; IOD: integrated optical density; T = topography distribution; N = lymph node metastasis; M = distant metastasis; AFP = alpha fetal protein

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