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Fig. 3 | BMC Cancer

Fig. 3

From: Germline variation networks in the PI3K/AKT pathway corresponding to familial high-incidence lung cancer pedigrees

Fig. 3

The germline SNP-containing genes in the PI3K/AKT pathway and pathways in cancer. a The number of germline SNP-containing genes in the two pathways. The colors and symbols are the same as in Fig. 2g. b Number of non-benign PI3K/AKT pathway SNPs recorded in ClinVar database. c Percentage of PI3K/AKT pathway SNPs which are found as somatic mutations in cancers (COSMIC database). d Percentage of “damaging” (change-of-funciton) PI3K/AKT SNPs, predicted by PROVEAN web server

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BMC Cancer

ISSN: 1471-2407

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