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Table 1 Proportion of B cells and its subpopulations (%) as detected by multicolor flow cytometry in 75 DLBCL patients bone marrow (N = 47) and peripheral blood (N = 54) samples at the time of diagnosis

From: High proportion of anergic B cells in the bone marrow defined phenotypically by CD21(−/low)/CD38- expression predicts poor survival in diffuse large B cell lymphoma

   

Bone marrow

Peripheral blood

Gated on

Cell population

Phenotype

N

Mean

SD

Min.

Max.

N

Mean

SD

Min.

Max.

%lymphocytes

B cells

CD19+

47

13.35

7.49

0.30

32.50

54

14.11

11.71

1.79

60.00

%lymphocytes

Memory

CD19+ CD27+

 

3.60

4.71

0.04

23.40

 

3.29

3.83

0.00

22.70

%B cells

lambda

lambda+

 

27.27

14.47

0.52

84.90

 

34.65

16.25

0.82

93.30

 

kappa

kappa+

 

42.77

17.78

1.13

76.10

 

47.24

16.47

0.56

74.70

 

Precursor

CD34+ CD10+

 

1.40

2.34

0.00

11.00

 

0.41

1.05

0.00

6.36

 

Transitional-e

CD34- CD10+

 

6.73

12.95

0.00

50.80

 

0.07

0.13

0.00

0.62

 

Transitional-d

CD21- CD38+

 

22.53

20.80

0.35

90.10

 

11.34

17.86

0.00

96.90

 

Transitional-a

CD10+ CD38+

 

9.64

15.03

0.00

71.10

 

0.68

1.13

0.00

4.81

 

Anergic

CD21(−/low)CD38-

 

24.21

26.20

2.35

97.20

 

21.63

16.61

0.60

95.50

  1. DLBCL Diffuse large B cell lymphoma