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Table 1 Main characteristics of the studies selected for the meta-analysis

From: Biomarker exploration of microRNA-203 as a promising substrate for predicting poor survival outcome in colorectal cancer

First author Year Country Ethnicity M/F N Age TNM stage Sample souce Methods Endogenous
control
Endpoints Median follow-up time
(months)
Hazard ratio
Schetter et al 2008 USA Non-Asians 66/18 84 65 I-IV Tissue RT-PCR U6 OS 68 3.10 (1.50–6.40)
Bovell et al 2013 USA Non-Asians 170/175 345 65 I-IV Tissue RT-PCR U6 OS 228 1.90 (1.05–3.42)
Tao et al 2014 China Asians 47/43 90 70 I-IV Tissue RT-PCR U6 OS 27 1.38 (0.77–2.48)
Deng et al. (Cohort 1) 2016 China Asians 39/33 72 50 I-IV Tissue RT-PCR U6 OS 84 0.62 (0.32–1.20)
Deng et al. (Cohort 2) 2016 China Asians 39/33 72 50 I-IV Serum RT-PCR U6 OS 84 0.36 (0.20–0.64)
Kingham et al. (Cohort 1) 2017 USA Non-Asians 57/34 91 59 I-IV Tissue RT-PCR miR-331 OS 192 1.92 (1.17–3.13)
Kingham et al. (Cohort 2) 2017 USA Non-Asians 31/15 46 56 I-IV Serum RT-PCR miR-331 OS 60 1.98 (1.14–3.42)
Takano et al 2017 Japan Asians 147/93 240 NA I-IV Serum RT-PCR miR-16 OS 54 2.27 (1.31–4.09)
Hur et al. (Cohort 1-tissue) 2017 Japan Asians 90/64 154 68 I-IV Tissue RT-PCR Cel-miR-39 OS 72 1.56 (0.80–3.05)
Hur et al. (Cohort 1-serum) 2017 Japan Asians 107/79 186 68 I-IV Serum RT-PCR Cel-miR-39 OS 72 2.14 (1.09–4.21)
Hur et al. (Cohort 1-serum) 2017 Japan Asians 87/57 144 68 I-IV Serum RT-PCR Cel-miR-39 OS 72 2.35 (1.34–4.12)
  1. Abbreviations: F female, M male, N number, OS overall survival