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Fig. 3 | BMC Cancer

Fig. 3

From: YB-1 transferred by gastric cancer exosomes promotes angiogenesis via enhancing the expression of angiogenic factors in vascular endothelial cells

Fig. 3

The influence of exosomes from YB-1-upregulated GC cells on the proliferation, apoptosis, migration and invasion of HUVECs. a MTT assays revealed that SGC-7901-OE-Exo promoted the proliferation of HUVECs. b Apoptosis assays using flow cytometry and (c) the corresponding quantitative analysis demonstrated that SGC-7901-OE-Exo reduced the apoptosis of HUVECs. d Scratch wound healing assays for HUVECs in different conditions. e The level of cell migration into the wound scratch was quantified as the wound healing area and compared to that of control group at 6 and 12 h. f The transwell pictures and (g, h) the quantitative data revealed significantly increased migration and invasion of HUVECs treated by SGC-7901-OE-Exo than the control group. (*, P < 0.05; **, P < 0.01)

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BMC Cancer

ISSN: 1471-2407

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