Table 1 Baseline characteristics
Characteristics | n (%) |
|---|---|
Total, N | 368(100) |
Tumor type | |
GBC | 73 (19.8) |
ICC | 74 (20.1) |
ECC | 221 (60.0) |
Age (years) | |
≤ 60 | 155 (42.1) |
> 60 | 213 (57.9) |
Sex | |
Female | 168 (45.7) |
Male | 200 (54.3) |
BMI at diagnosis, kg/m2 | |
< 18.5 | 19 (5.2) |
18.5–22.9 | 128 (34.8) |
≥ 23 | 177 (48.1) |
NA | 44 (12.0) |
Alcohol | |
Yes | 90 (24.5) |
No | 278 (75.5) |
Fatty liver | |
Yes | 27 (7.3) |
No | 341 (92.7) |
Jaundice | |
Yes | 219 (59.5) |
No | 149 (40.5) |
Tumor size, cm | |
D ≤ 2 | 180 (50.6) |
2 < D ≤ 3 | 85 (23.1) |
3 < D ≤ 4 | 35 (9.5) |
D > 4 | 56 (15.2) |
NA | 12 (3.3) |
Lymph node metastasis | |
Yes | 122 (33.2) |
No | 246 (66.8) |
Extrahepatic involvement | |
Yes | 252 (68.5) |
No | 116 (31.5) |
Intrahepatic involvement | |
Yes | 111 (30.2) |
No | 257 (69.8) |
Gallbladder involvement | |
Yes | 91 (24.7) |
No | 277 (75.3) |
AJCC 8th TNM stage | |
I | 133 (36.1) |
II | 120 (32.6) |
III | 115 (31.3) |
Tumor differentiation | |
Undifferentiation | 2 (0.5) |
Low | 36 (9.8) |
Low-moderate | 98 (26.6) |
Moderate | 102 (27.7) |
Moderate-high | 28 (7.6) |
High | 102 (27.7) |
Radical cure | |
Yes | 232 (63.0) |
No | 136 (37.0) |
R0 | |
Yes | 248 (67.4) |
No | 120 (32.6) |
TC level, mmol/L | |
≤ 7.28 | 301 (81.8) |
> 7.28 | 67 (18.2) |
TG level, mmol/L | |
≤ 3.14 | 301 (81.8) |
> 3.14 | 67 (18.2) |
HDL level, mmol/L | |
≤ 0.95 | 205 (55.7) |
> 0.95 | 163 (44.3) |
LDL level, mmol/L | |
≤ 1.96 | 41 (11.1) |
> 1.96 | 327 (88.9) |
TC/HDL | |
≤ 10.08 | 256 (69.6) |
> 10.08 | 112 (30.4) |
TG/HDL | |
≤ 4.16 | 258 (70.1) |
> 4.16 | 110 (29.9) |
ApoA1 level, g/L | |
≤ 1.11 | 166 (45.1) |
> 1.11 | 150 (40.8) |
NA | 52 (14.1) |
ApoB level, g/L | |
≤ 0.90 | 210 (57.1) |
> 0.90 | 105 (28.5) |
NA | 53 (14.4) |
Lipoprotein level, mg/L | |
≤ 72 | 152 (41.3) |
> 72 | 118 (32.1) |
NA | 98 (26.6) |
Albumin level, g/L | |
≤ 35 | 59 (16.0) |
> 35 | 305 (82.9) |
NA | 4 (1.1) |
ALT level, U/L | |
≤ 40 | 116 (31.5) |
> 40 | 252 (68.5) |
AST level, U/L | |
≤ 40 | 130 (35.3) |
> 40 | 233 (63.3) |
NA | 5 (1.4) |
GGT level, U/L | |
≤ 45 | 72 (19.5) |
> 45 | 291 (79.1) |
NA | 5 (1.4) |
ALP level, U/L | |
≤ 135 | 121 (32.9) |
> 135 | 242 (65.7) |
NA | 5 (1.4) |
LDH level, U/L | |
≤ 250 | 300 (81.5) |
> 250 | 61 (16.6) |
NA | 7 (1.9) |
TBIL level, umol/L | |
≤ 17.1 | 113 (30.7) |
> 17.1 | 255 (69.3) |
CA199 level, U/mL | |
≤ 37 | 94 (25.5) |
> 37 | 263 (71.5) |
NA | 11 (3.0) |
Overall survival, months | 21.9 (11.0–39.0) |