In vivo optical cellular diagnosis for uterine cervical or vaginal intraepithelial neoplasia using flexible gastrointestinal endocytoscopy -a prospective pilot study-

Table 3 Correlations between ECS classification and histological diagnosis (including the most prominent sites and surrounding area)

Biopsy	< CIN 3 < VAIN 3, n	≥ CIN 3 ≥ VAIN 3, n	Total, n
ECS classification	< CIN 3 < VAIN 3, n	≥ CIN 3 ≥ VAIN 3, n	Total, n
ECS 1–3, n	4	2	26
ECS 4, 5, n	5	23	28
Total, n	29	25	54

CIN cervical intraepithelial neoplasia, VAIN vaginal intraepithelial neoplasia, ECS endocytoscopy
Sensitivity; 92.0 (79.9–97.6), specificity; 82.8 (72.4–87.5), PPV; 82.1 (71.4–87.1), NPV; 92.3 (80.7–97.6), accuracy; 87.0 (75.9–92.2) (95% CI)

ISSN: 1471-2407