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Fig. 6 | BMC Cancer

Fig. 6

From: Therapeutic potential of a novel prodrug of green tea extract in induction of apoptosis via ERK/JNK and Akt signaling pathway in human endometrial cancer

Fig. 6

Apoptotic and microvessel development in endometrial carcinoma xenograft tumors after ProEGCG treatment. Haemotoxylin & eosin staining, TUNEL assay, caspase-3 and CD34 in (a) Rl95–2 and (b) AN3 CA xenograft tumors were analyzed by immunohistochemistry (magnification 200x). c, d The expression levels of CD34-postive cells were quantified. e Hierarchical clustering shows differential regulation of BAG1, NOD1 and NAIP (pink tree branch, yellow box) after EGCG and ProEGCG treatments in human EC cell xenografts. f Quantitative analysis by real-time PCR validated the differential expression of NOD1, NAIP and BAG1 after EGCG and ProEGCG treatment in human EC cell lines. Data are presented as mean ± S.E.M. Significant differences from control: *P < 0.05 and **P < 0.01

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BMC Cancer

ISSN: 1471-2407

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