Table 3 Anogenital SPCs in CIN 2–3 LLETZ treated women. A comparison between literature and our study data
From: Risk of HPV-related extra-cervical cancers in women treated for cervical intraepithelial neoplasia
Author | Year | First lesion | Value | Vulva | Vagina | Anus |
|---|---|---|---|---|---|---|
Evans [26] | 2003 | CIN 3 | SIR | 4.4 | 18.5 | 5.9 |
Kalliala [6] | 2005 | CIN 1–3 | SIR | 4.1 | 12 | 5.7 |
Edgren [9] | 2007 | CIN 3 | IRR | 2.2 | 6.7 | 4.7 |
Strander [22] | 2007 | CIN 3 | RR | Â | 6.8 | Â |
Saleem [12] | 2007 | CIN3 | SIR | – | – | 16.4 |
|  |  | SCC | SIR | – | – | 6.2 |
Tatti [27] | 2012 | CIN 2–3 | OR | – | – | 1.91 |
Gaudet [10] | 2014 | CIN 2 | SIR | 1.47 | 3.61 | 0.89 |
| Â | Â | CIN 3 | SIR | 3.79 | 8.53 | 2.28 |
|  |  | CIN2–3 | SIR | 2.9 | 6.65 | 1.75 |
Sand [11] | 2016 | CIN 2 | RR | 2.5 | 8.1 | 2.9 |
| Â | Â | CIN 3 | RR | 4 | 17.1 | 4.2 |
Ebisch [8] | 2017 | CIN 3 | IRR | 4.97 | 86.08 | 3.85 |
Suk [23] | 2018 | SCC | SIR | 3.8 | 17.3 | 2.3 |
Acevedo Fontánez [14] | 2018 | SCC | SIR | – | – | 51.6 |
Wang [16] | 2020 | SCC | SIR | 2.29 | 1.85 | 1.41 |
Our study |  | CIN 2–3 | SIR | 1.7 | 12.4 | 1.8 |