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Table 3 Altered gene expression associated with exposure of cells to drugs, TXT and/or Ramucirumab

From: Distinctive roles of syntaxin binding protein 4 and its action target, TP63, in lung squamous cell carcinoma: a theranostic study for the precision medicine

Genes TXT Ramucirumab TXT + Ramucirumab
m_value p_value q_value m_value p_value q_value m_value p_value q_value
LK-2
STXBP4 −0.0220 0.8760 1.0000 −0.0330 0.8610 1.0000 −0.0970 0.5800 1.0000
TP63 1.0480 0.2390 1.0000 0.7020 0.4630 1.0000 0.1620 1.0000 1.0000
TP53 −0.0550 0.3770 1.0000 0.0710 0.6290 1.0000 −0.0180 0.9000 1.0000
KDR 0.0960 0.6650 1.0000 −0.0440 0.8800 1.0000 0.2760 0.2430 1.0000
TUBB3 0.0530 0.4340 1.0000 0.0560 0.7100 1.0000 0.0490 0.7310 1.0000
STMN1 0.0670 0.2820 1.0000 0.0860 0.5560 1.0000 0.1780 0.1970 1.0000
CD274 0.2700 0.3117 1.0000 0.1174 0.7383 1.0000 0.3239 0.2586 1.0000
RERF-LC-AI
STXBP4 0.2310 0.6750 1.0000 0.0840 0.9040 1.0000 −0.0240 0.9760 1.0000
TP63 2.5270 0.0001 0.0270 1.8600 0.0110 0.5420 2.0460 0.0087 0.4560
TP53 0.1150 0.8330 1.0000 0.0880 0.8950 1.0000 0.0850 0.9060 1.0000
KDR 1.3150 0.2730 1.0000 −0.2550 1.0000 1.0000 −0.1620 1.0000 1.0000
TUBB3 0.2040 0.6940 1.0000 0.8610 0.1720 1.0000 0.7020 0.3030 1.0000
STMN1 0.0420 0.9350 1.0000 1.6410 0.0104 0.5330 1.2510 0.0690 1.0000
CD274 −1.3328 0.0116 0.5476 −1.5704 0.0144 0.6156 −1.5697 0.0240 0.7406
  1. m_value, log2 fold change (with and without treatment); q_value, false discovery rate (FDR)