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Table 4 Univariate and multivariate Cox regression analyses for 38G and CAPRA-S in the validation (TCGA) cohort

From: A 38-gene model comprised of key TET2-associated genes shows additive utility to high-risk prostate cancer cases in the prognostication of biochemical recurrence

 

Hazard ratio

2.50%

97.50%

log-rank p-value

Univariate

 38G

2.458

1.14

5.3

0.0218

 CAPRA-S

2.209

1.441

3.387

2.77E-04

Multivariate (low vs intermediate vs high risk CAPRA-S)

 38G

2.222

0.976

5.059

0.0571

 CAPRA-S

2.073

1.344

3.198

9.81E-04

Multivariate (high-risk vs. low/intermediate-risk CAPRA-S)

 38G

2.799

1.498

5.229

0.0013

 CAPRA-S

2.362

1.039

5.37

4.03E-02

  1. CAPRA-S has been assessed as per categorical risk classification: low, intermediate, and high-risk
  2. Multivariate analysis 1: HR represents increased risk in intermediate-risk cases as compared to low-risk, or in high-risk cases as compared to intermediate-risk
  3. Multivariate analysis 2: HR represents increased risk in high-risk cases as compared to low- or intermediate-risk cases
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BMC Cancer

ISSN: 1471-2407

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