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Table 2 Comparison of HPV gene expression between stages, types of lung cancer, and controls

From: The association between HPV gene expression, inflammatory agents and cellular genes involved in EMT in lung cancer tissue

Cancer characteristic E2 E6 E7
Controls (n = 48) 5.82 ± 2.48 (1) 8.36 ± 3.14 (1) 8.64 ± 4.30 (1)
Stages of Cancer (n = 102) IA 4.0 ± 1.27 (0.68) 9.0 ± 1.2 (1.07) 8.0 ± 1.89 (0.92)
IB 5 ± 1.0 (0.86) 3.0 ± 1.75 (0.36) 5.0 ± 0.57 (0.58)
IIA 8 ± 5.29 (1.37) 8 ± 2.45 (0.95) 9.75 ± 4.50 (1.13)
IIB 6.83 ± 2.32 (1.17) 9.1 ± 4.77 (1.09) 10.8 ± 6.59 (1.25)
IIIA 4.3 ± 3.02 (0.74) 8.54 ± 3.75 (1.02) 11.23 ± 4.95 (1.30)
IIIB 6.58 ± 4.08 (1.13) 8.13 ± 5.23 (0.97) 10.13 ± 5.17 (1.17)
IV 6.0 ± 3.83 (1.03) 12.33 ± 4.66 (1.47) 13.56 ± 5.13 (1.57)
P-value 0.585 0.301 0.643
Types of Cancer (n = 102) Adenocarcinoma 5.83 ± 3.69 (1) 9.67 ± 4.99 (1.17) 11.94 ± 4.93 (1.38)
Squamous-cell carcinoma 6.39 ± 3.69 (1.1) 8.63 ± 4.70 (1.03) 10.17 ± 5.57 (1.18)
Small-cell lung carcinoma 3.67 ± 1.15 (0.63) 9.0 ± 3.28 (1.07) 11.67 ± 5.09 (1.35)
P-value 0.466 0.762 0.504
  1. Geometric Mean ± Standard Deviation (fold change), control group was as a reference group