Variable | T790M mutation | ||
---|---|---|---|
Positive (n = 11) | Negative (n = 47) | Total | |
Original mutation | |||
Absent | 1 | 38 | 39 |
Present | 10 | 9 | 19 |
Bone metastases | |||
Absent | 1 | 39 | 40 |
Present | 10 | 8 | 18 |
Enlargement of Tumor size | |||
< 12 mm | 7 | 7 | 14 |
12 mm ≤ | 4 | 40 | 44 |
Brain metastases | |||
Absent | 4 | 38 | 42 |
Present | 7 | 9 | 16 |
Detection of New tumor lesion | |||
< 4 | 4 | 38 | 42 |
4 ≤ | 7 | 9 | 16 |
Detection of New metastatic organ | |||
0 | 6 | 36 | 42 |
1 | 2 | 7 | 9 |
2 | 0 | 3 | 3 |
3 | 1 | 1 | 2 |
4 | 2 | 0 | 2 |
New minor site metastases | |||
Absent | 8 | 45 | 53 |
Present | 3 | 2 | 5 |
Hepatic metastases | |||
Absent | 8 | 44 | 52 |
Present | 3 | 3 | 6 |
Minor site metastases | |||
Absent | 8 | 44 | 52 |
Present | 3 | 3 | 6 |
Mutation site at initial diagnosis | |||
Exon19 Deletion | 4 | 41 | 45 |
L858R | 7 | 6 | 13 |
New hepatic metastases | |||
Absent | 9 | 45 | 54 |
Present | 2 | 2 | 4 |