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Table 2 The effect of MIR17HG variants on the risk of glioma

From: Genetic variants in MIR17HG affect the susceptibility and prognosis of glioma in a Chinese Han population

SNP ID Allele/Genotype Control Case OR (95% CI) p FDR-p
rs17735387 G 829 964 1   
A 175 220 1.08 (0.87–1.35) 0.486 0.778
GG 341 395 1   
GA 147 174 1.02 (0.79–1.33) 0.871 0.909
AA 14 23 1.42 (0.72–2.80) 0.315 0.756
GA + AA 161 197 1.06 (0.82–1.36) 0.672 0.806
Additive / / 1.08 (0.87–1.34) 0.488 0.732
rs72640334 C 916 1070 1   
A 86 110 1.10 (0.81–1.47) 0.547 0.772
CC 418 487 1   
CA 80 96 1.03 (0.74–1.43) 0.860 0.938
AA 3 7 2.01 (0.51–7.83) 0.316 0.689
CA + AA 83 103 1.07 (0.78–1.46) 0.696 0.795
Additive / / 1.09 (0.82–1.47) 0.550 0.733
rs7318578 A 714 768 1   
C 290 412 1.32 (1.10–1.58) 2.63 × 10−3 0.032
AA 257 294 1   
AC 200 180 0.79 (0.61–1.02) 0.073 0.438
CC 45 116 2.25 (1.54–3.31) 3.18 × 10–5* 0.001
AC + CC 245 296 1.06 (0.83–1.34) 0.654 0.826
Additive / / 1.26 (1.07–1.49) 6.23 × 10−3 0.050
rs7336610 T 527 602 1   
C 475 580 1.07 (0.90–1.27) 0.438 0.809
TT 141 144 1   
TC 245 314 1.26 (0.94–1.67) 0.119 0.476
CC 115 133 1.13 (0.80–1.59) 0.477 0.818
TC + CC 360 447 1.22 (0.93–1.59) 0.157 0.419
Additive / / 1.07 (0.90–1.27) 0.433 0.866
rs75267932 A 879 1061 1   
G 125 123 0.82 (0.63–1.06) 0.130 0.446
AA 385 479 1   
AG 109 103 0.76 (0.56–1.03) 0.073 0.438
GG 8 10 1.01 (0.39–2.58) 0.988 0.988
AG + GG 117 113 0.78 (0.58–1.04) 0.089 0.427
Additive / / 0.82 (0.63–1.07) 0.138 0.414
  1. Abbreviations: SNP Single nucleotide polymorphism, OR Odds ratio, CI Confidence interval, FDR False discovery
  2. p values were calculated by logistic regression analysis with adjustments for age and gender
  3. Bold p < 0.05 means the data is statistically significant
  4. * After Bonferroni correction [p < 0.05/(5 × 4)] means the data is statistically significant