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Table 2 Overall comparison of SEQ detected and HRM

From: Somatic mutation detection efficiency in EGFR: a comparison between high resolution melting analysis and Sanger sequencing

HRM detected SEQ Detected p value Sensitivity Specificity PPV NPV Accuracy
Positive (%) Negative (%)
Positive 67 (80.7) 16 (19.3) <‚ÄČ 0.001 100% 67.3% 80.7% 100% 86%
Negative 0 (0) 33 (100)