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Table 2 Overall comparison of SEQ detected and HRM

From: Somatic mutation detection efficiency in EGFR: a comparison between high resolution melting analysis and Sanger sequencing

HRM detected

SEQ Detected

p value

Sensitivity

Specificity

PPV

NPV

Accuracy

Positive (%)

Negative (%)

Positive

67 (80.7)

16 (19.3)

<  0.001

100%

67.3%

80.7%

100%

86%

Negative

0 (0)

33 (100)

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BMC Cancer

ISSN: 1471-2407

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