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Table 2 Association between GLUT-1 intensity and extension and clinicopathological variables in pancreatic cancer patients

From: GLUT-1 as a predictor of worse prognosis in pancreatic adenocarcinoma: immunohistochemistry study showing the correlation between expression and survival

Patient characteristics

Weak intensity

n= 23

Strong intensity

n= 16

P value

Age

< 60

5 (21.7%)

2 (12.5%)

.678

> 60

18 (78.3%)

14 (87.5%)

 

Gender

Male

14 (60.9%)

9 (56.3%)

1

Female

9 (39.1%)

7 (43.8%)

 

T

T1-T2

4 (17.4%)

2 (12.5%)

1

T3

19 (82.6%)

14 (87.5%)

 

N

N0

12 (52.2%)

6 (37.5%)

.516

N1

11 (47.8%)

10 (62.5%)

 

Differentiation

Good

19 (86.4%)

9 (56.3%)

.062

Poor

3 (13.6%)

7 (43.8%)

 

Microvascular

invasion

No

0

0

1

Yes

9 (100%)

11 (100%)

 

Lymphatic

invasion

No

9 (45%)

5 (31.3%)

.501

Yes

11 (55%)

11 (68.8%)

 

Perineural

invasion

No

3 (15%)

2 (12.5%)

1

Yes

17 (85%)

14 (87.5%)

 

LNR 20

No

4 (17.4%)

6 (37.5%)

.264

Yes

19 (82.6%)

10 (62.5%)

 

Resection margin

R0

12 (52.2%)

6 (37.5%)

.516

R1

11 (47.8%)

10 (62.5%)

 

Complications

Clavien-D

< 3

14 (66.7%)

12 (75%)

.723

> 3

7 (33.3%)

4 (25%)

 

Recurrence

No

7 (30.4%)

2 (12.5%)

.262

Yes

16 (69.6%)

14 (87.5%)

 

DFS (m)

 

27.14

23.54

.300

OS(m)

 

41.36

37.57

.628

Patient characteristics

 

Low extension

n= 11

High extension

n= 28

P value

Age

< 60

2 (18.2%)

5 (17.9%)

1

> 60

9 (81.8%)

23 (82.1%)

 

Gender

Male

8 (72.7%)

15 (53.6%)

.471

Female

3 (27.3%)

13 (46.4%)

 

T

T1-T2

4 (36.4%)

2 (7.1%)

.042*

T3

7 (63.6%)

26 (92.9%)

 

N

N0

8 (72.7%)

10 (35.7%)

.072

N1

3 (27.3%)

18 (64.3%)

 

Differentiation

Good

20 (83.3%)

8 (57.1%)

1

Poor

4 (16.7%)

6 (42.9%)

 

Microvascular

invasion

No

0

0

1

Yes

8 (100%)

12 (100%)

 

Lymphatic

invasion

No

4 (40%)

10 (38.5%)

1

Yes

6 (60%)

16 (61.5%)

 

Perineural

invasion

No

2 (20%)

3 (11.5%)

.603

Yes

8 (80%)

23 (88.5%)

 

LNR 20

No

11 (100%)

18 (64.3%)

.037*

Yes

0

10 (35.7%)

 

Resection margin

R0

5 (45.5%)

13 (46.4%)

1

R1

6 (54.5%)

15 (53.6%)

 

Complications

Clavien-D

< 3

8 (72.7%)

18 (69.2%)

1

> 3

3 (27.3%)

8 (30.8%)

 

Recurrence

No

5 (45.5%)

4 (14.3%)

.085

Yes

6 (54.5%)

24 (85.7%)

 

DFS (m)

 

54.46

17.58

.048*

OS(m)

 

56.37

32.26

.128

  1. Bold*: statistically significant