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Table 2 Association between GLUT-1 intensity and extension and clinicopathological variables in pancreatic cancer patients

From: GLUT-1 as a predictor of worse prognosis in pancreatic adenocarcinoma: immunohistochemistry study showing the correlation between expression and survival

Patient characteristics Weak intensity
n= 23
Strong intensity
n= 16
P value
Age < 60 5 (21.7%) 2 (12.5%) .678
> 60 18 (78.3%) 14 (87.5%)  
Gender Male 14 (60.9%) 9 (56.3%) 1
Female 9 (39.1%) 7 (43.8%)  
T T1-T2 4 (17.4%) 2 (12.5%) 1
T3 19 (82.6%) 14 (87.5%)  
N N0 12 (52.2%) 6 (37.5%) .516
N1 11 (47.8%) 10 (62.5%)  
Differentiation Good 19 (86.4%) 9 (56.3%) .062
Poor 3 (13.6%) 7 (43.8%)  
Microvascular
invasion
No 0 0 1
Yes 9 (100%) 11 (100%)  
Lymphatic
invasion
No 9 (45%) 5 (31.3%) .501
Yes 11 (55%) 11 (68.8%)  
Perineural
invasion
No 3 (15%) 2 (12.5%) 1
Yes 17 (85%) 14 (87.5%)  
LNR 20 No 4 (17.4%) 6 (37.5%) .264
Yes 19 (82.6%) 10 (62.5%)  
Resection margin R0 12 (52.2%) 6 (37.5%) .516
R1 11 (47.8%) 10 (62.5%)  
Complications
Clavien-D
< 3 14 (66.7%) 12 (75%) .723
> 3 7 (33.3%) 4 (25%)  
Recurrence No 7 (30.4%) 2 (12.5%) .262
Yes 16 (69.6%) 14 (87.5%)  
DFS (m)   27.14 23.54 .300
OS(m)   41.36 37.57 .628
Patient characteristics   Low extension
n= 11
High extension
n= 28
P value
Age < 60 2 (18.2%) 5 (17.9%) 1
> 60 9 (81.8%) 23 (82.1%)  
Gender Male 8 (72.7%) 15 (53.6%) .471
Female 3 (27.3%) 13 (46.4%)  
T T1-T2 4 (36.4%) 2 (7.1%) .042*
T3 7 (63.6%) 26 (92.9%)  
N N0 8 (72.7%) 10 (35.7%) .072
N1 3 (27.3%) 18 (64.3%)  
Differentiation Good 20 (83.3%) 8 (57.1%) 1
Poor 4 (16.7%) 6 (42.9%)  
Microvascular
invasion
No 0 0 1
Yes 8 (100%) 12 (100%)  
Lymphatic
invasion
No 4 (40%) 10 (38.5%) 1
Yes 6 (60%) 16 (61.5%)  
Perineural
invasion
No 2 (20%) 3 (11.5%) .603
Yes 8 (80%) 23 (88.5%)  
LNR 20 No 11 (100%) 18 (64.3%) .037*
Yes 0 10 (35.7%)  
Resection margin R0 5 (45.5%) 13 (46.4%) 1
R1 6 (54.5%) 15 (53.6%)  
Complications
Clavien-D
< 3 8 (72.7%) 18 (69.2%) 1
> 3 3 (27.3%) 8 (30.8%)  
Recurrence No 5 (45.5%) 4 (14.3%) .085
Yes 6 (54.5%) 24 (85.7%)  
DFS (m)   54.46 17.58 .048*
OS(m)   56.37 32.26 .128
  1. Bold*: statistically significant