Skip to main content
Fig. 4 | BMC Cancer

Fig. 4

From: Anti-cancer agent 3-bromopyruvate reduces growth of MPNST and inhibits metabolic pathways in a representative in-vitro model

Fig. 4

Activity of NADH dehydrogenase in PA28y overexpressing (B8y) and control cells (B8vc) after 3-BrPA treatment and nutrient deprivation. c(3-BrPA) – concentration of 3-BrPA; ∆CUnorm – normalized difference of colorimetric units. a Mean values of normalized differences in CU ± SEM are presented. Results under normal conditions (10% FBS) are indicated by full lines; under serum free conditions (0.2% FBS), cell lines are marked with an asterisk and results are displayed by dotted lines. There are no concentration ranges with significant differences (p < 0.05) in NADH dehydrogenase activity compared to starved cells. b Correlations between NADH dehydrogenase activity and agent concentration as regression lines. For details of statistics see Additional file 3

Back to article page