Fig. 5
From: USP6NL mediated by LINC00689/miR-142-3p promotes the development of triple-negative breast cancer
MiR-142-3p suppression or USP6NL overexpression abolishes the effect of LINC00689 silence on TNBC cell proliferation and apoptosis. a. The expression of LINC00689 was measured by RT-qPCR in the context of LINC00689 knockdown. b. RT-qPCR determined the expression of USP6NL in TNBC cells transfected with pcDNA3.1 or pcDNA3.1/USP6NL. c. The colony formation assay detected the effect of inhibited miR-142-3p or upregulated USP6NL on LINC00689 silence-mediated cell proliferation. d-f. Flow cytometry analysis, JC-1 assay and TUNEL assay evaluated the apoptosis of cells under diverse conditions. The X axis of the FACS dot plots in Fig. 5d meant cells labelled with FITC and the Y axis indicated cells dyed by PI. **P < 0.01