Skip to main content

Table 2 Comparison of the two groups of patients in terms of demographic and preoperative characteristics

From: Defining the optimal bilirubin level before hepatectomy for hilar cholangiocarcinoma

  Bilirubin
≤75 μmol/L
(n = 82)
Bilirubin
> 75 μmol/L
(n = 8)
P value
Age (years) 66.0 (29–85) 69.0 (56–72) 0.696
Male: Female 55: 27 8: 0 0.125
Comorbidity 38 (46.3%) 3 (37.5%) 0.914
 Heart 35 (42.7%) 2 (25%) 0.553
 Lung 5 (6.1%) 1 (12.5%) 1.000
 Renal 1 (1.2%) 0 (0%) 1.000
 Diabetes mellitus 15 (18.3%) 1 (12.5%) 1.000
Child-Pugh class    0.159
 A 37 (45.1%) 1 (12.5%)  
 B 45 (54.9%) 7 (87.5%)  
Pre-drainage bilirubin (μmol/L) 98.0 (8–576) 124.0 (28–492) 0.673
Post-drainage bilirubin (μmol/L) 20.5 (7–73) 95.5 (76–366) < 0.001a
Creatinine (μmol/L) 76.5 (40–148) 81.0 (61–130) 0.391
Albumin (g/L) 37.0 (27–51) 37.0 (26–43) 0.312
International normalized ratio 1.0 (0.9–1.4) 1.0 (0.9–1.2) 0.473
Platelet count (× 109/L) 288.0 (71–561) 342.0 (166–699) 0.750
Carcinoembryonic antigen (ng/mL) 2.65 (0.3–16) 3.0 (1.8–10.0) 0.528
Indocyanine green retention rate at 15 min (%) (n = 38) 10.55 (3–20.1) 20.6 (7.9–32.5) 0.148
Aspartate transaminase (U/L) 71.5 (14–748) 56.5 (45–337) 0.771
Alanine transaminase (U/L) 101.5 (9–1178) 106.0 (37–481) 0.837
Neoadjuvant chemotherapy 1 (1.6%) 0 (0%) 1.000
Portal vein embolization 28 (34.1%) 2 (25.0%) 0.896
Time from drainage procedure to hepatectomy (months) 1.84 (0.2–4.7) 1.35 (0.3–3.1) 0.772
ERCP 69 (84.1%) 7 (87.5%) 1.000
ERCP purpose    0.939
 No 13 (15.9%) 1 (12.5%)  
 Diagnosis 53 (64.6%) 5 (62.5%)  
 Complication 1 (1.2%) 0 (0%)  
 Diagnosis + Complication 15 (18.3%) 2 (25%)  
ERCP complication    0.615
 No 57 (69.5%) 6 (75%)  
 Cholangitis 10 (12.2%) 2 (25%)  
 Pancreatitis 11 (13.4%) 0 (0%)  
 Deranged liver function tests 2 (2.4%) 0 (0%)  
 Slip 1 (1.2%) 0 (0%)  
 Cholangitis + Pancreatitis 1 (1.2%) 0 (0%)  
PTBD 49 (59.8%) 5 (62.5%) 1.000
PTBD purpose    0.755
 No 34 (41.5%) 3 (37.5%)  
 Diagnosis 30 (36.6%) 4 (50%)  
 Complication 4 (4.9%) 0 (0%)  
 Diagnosis + Complication 14 (17.1%) 1 (12.5%)  
PTBD complication    0.722
 No 66 (80.5%) 7 (87.5%)  
 Cholangitis 4 (4.9%) 1 (12.5%)  
 Cholecystitis 1 (1.2%) 0 (0%)  
 Severe pancreatitis precluding management 1 (1.2%) 0 (0%)  
 Slip 6 (7.3%) 0 (0%)  
 Cholangitis + Slip 4 (4.9%) 0 (0%)  
  1. Data are shown as number of patient (percent) or median (range) or ratio
  2. astatistically significant