Table 3 Analysis of CD4+ T cells, CD8+ T cells and B cells subpopulations by flow cytometry
Lymphocyte subpopulations | Cases | Controls | p |
|---|---|---|---|
CD4+ T cells subpopulationsa | |||
Naïve (%) | 33.1 (15.9–44.3) | 39.2 (31.4–55.7) | 0.026 |
Central Memory (%) | 38.7 (24.4–48.6) | 31.9 (24.4–40.9) | 0.569 |
Effector Memory (%) | 18.1 (13.5–25.8) | 9.8 (6.8–11.6) | 0.001 |
CD4+ CD28+ (%) | 91.7 (85.4–97.3) | 98.5 (92.8–99.2) | 0.070 |
CD4+ CD57+ (%) | 65.1 (21.2–80.0) | 38.1 (24.0–70.6) | 0.215 |
CD8+ T cells subpopulationsb | |||
Naïve (%) | 17.6 (8.3–27.1) | 27.0 (19.8–41.1) | 0.039 |
Central Memory (%) | 2.2 (1.4–4.4) | 4.1 (2.5–7.2) | 0.079 |
Effector Memory (%) | 34.0 (21.1–44.1) | 31.8 (21.4–37.8) | 0.535 |
CD8+ 45RA+ (%) | 60.9 (40.0–67.6) | 63.6 (46.8–73.8) | 0.717 |
CD8+ CD28+ (%) | 83.5 (57.2–91.7) | 83.7 (57.1–93.2) | 0.959 |
CD8+ CD57 (%) | 32.6 (18.2–40.1) | 20.2 (14.3–26.5) | 0.088 |
CD8+ CD45RA+ CD28- (%) | 16.8 (9.0–40.4) | 18.45 (7.5–34.4) | 0.605 |
CD8+ CD45RA+ CD57+ (%) | 41.6 (22.2–55.6) | 24.7 (10.1–32.2) | 0.015 |
B cells subpopulationsc | |||
Naïve (%) | 75.9 (64.3–87.5) | 71.0 (65.3–77.8) | 0.587 |
Memory (%) | 18.2 (8.0–23.4) | 27.8 (22.3–31.8) | 0.017 |
Plasmablasts (%) | 0.5 (0.1–1.1) | 0.2 (0.1–0.4) | 0.163 |