Variable | Odds Ratio (95% CI) Low RS | P-Value | Odds Ratio (95% CI) Intermediate RS | P-Value |
---|---|---|---|---|
Year of Diagnosis | ||||
2010 | Ref | Ref | Ref | Ref |
2011 | 0.68 (0.21–2.17) | 0.50 | 1.17 (0.45–3.04) | 0.75 |
2012 | 0.48 (0.14–1.72) | 0.25 | 2.23 (0.82–6.06) | 0.11 |
2013 | 0.34 (0.10–1.17) | 0.08 | 1.10 (0.41–2.95) | 0.84 |
2014 | 0.40 (0.12–1.39) | 0.14 | 0.67 (0.26–1.72) | 0.40 |
2015 | 0.21 (0.05–0.86) | 0.03* | 1.07 (0.41–2.76) | 0.89 |
2016 | 0.25 (0.06–0.94) | 0.04* | 1.10 (0.39–3.10) | 0.85 |
Patient Age at Diagnosis (Years) | ||||
< 50 | Ref | Ref | Ref | Ref |
50–59 | 0.67 (0.30–1.50) | 0.32 | 0.59 (0.31–1.13) | 0.11 |
60–69 | 0.17 (0.06–0.49) | < 0.01** | 0.29 (0.14–0.59) | < 0.01** |
> 69 | 0.08 (0.02–0.45) | < 0.01** | 0.10 (0.03–0.33) | < 0.01** |
Grade | ||||
I | Ref | Ref | Ref | Ref |
II | 1.48 (0.58–3.73) | 0.40 | 2.00 (1.06–3.80) | 0.03* |
III/IV | 7.80 (2.62–23.27) | < 0.01** | 2.37 (1.10–5.11) | 0.02* |
Unknown | 0.00 (0.00-Inf) | 0.99 | 0.00 (0.00-Inf) | 0.99 |
LN Status | ||||
Negative | Ref | Ref | Ref | Ref |
Positive | 5.84 (2.61–13.05) | < 0.01** | 1.93 (0.92–4.05) | 0.08 |
Unknown | 2.91 (0.25–34.27) | 0.38 | 0.50 (0.04–6.96) | 0.60 |
Tumor Size (mm) | ||||
0.1–19 | Ref | Ref | Ref | Ref |
20–39 | 0.96 (0.38–2.41) | 0.93 | 1.26 (0.55–2.88) | 0.58 |
> 40 | 8.16 (2.37–28.06) | < 0.01** | 0.94 (0.19–4.62) | 0.94 |
Unknown | 0.00 (0.00-Inf) | 0.99 | 0.79 (0.07–9.12) | 0.85 |
Clinical Stage | ||||
1 | Ref | Ref | Ref | Ref |
2 | 2.96 (1.10–7.98) | 0.03* | 2.59 (1.04–6.47) | 0.04* |
3 / 4 | 6.22 (1.18–32.74) | 0.03* | 0.36 (0.01–9.58) | 0.53 |
MD Clinical Experience (Years) | ||||
< 10 | Ref | Ref | Ref | Ref |
10–19 | 2.56 (0.26–25.28) | 0.41 | 0.75 (0.21–2.64) | 0.65 |
20–29 | 4.31 (0.44–41.94) | 0.20 | 1.61 (0.44–5.88) | 0.46 |
> 29 | 7.71 (0.75–79.43) | 0.08 | 2.02 (0.55–7.48) | 0.28 |
MD Gender | ||||
Female | Ref | Ref | Ref | Ref |
Male | 0.39 (0.17–0.88) | 0.02* | 0.73 (0.42–1.27) | 0.26 |
Patient Volume | 0.98 (0.95–1.00) | 0.08 | 1.01 (0.99–1.02) | 0.40 |
Average Patient Age | ||||
< 65 Years | Ref | Ref | Ref | Ref |
> 65 Years | 0.59 (0.13–2.74) | 0.50 | 0.76 (0.23–2.53) | 0.65 |
ODX RS | 0.98 (0.96–1.00) | 0.15 | 1.33 (1.22–1.44) | < 0.01** |