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Table 3 Multivariable regression odds ratios for receiving ODX

From: Patient and physician factors associated with Oncotype DX and adjuvant chemotherapy utilization for breast cancer patients in New Hampshire, 2010–2016

Variable

Odds Ratio (95% CI)

P-Value

Year of Diagnosis

 2010

Ref

Ref

 2011

1.00 (0.76–1.31)

0.99

 2012

1.00 (0.76–1.31)

0.99

 2013

1.00 (0.76–1.31)

0.98

 2014

1.05 (0.80–1.36)

0.73

 2015

1.05 (0.80–1.36)

0.73

 2016

1.09 (0.83–1.43)

0.54

Patient Age at Diagnosis (Years)

 < 50

Ref

Ref

 50–59

1.04 (0.86–1.27)

0.66

 60–69

0.97 (0.79–1.18)

0.75

 > 69

0.45 (0.35–0.58)

< 0.01**

Marital Status

 Single, Divorced, Widowed

Ref

Ref

 Married

1.22 (1.05–1.41)

< 0.01**

 Unknown

1.12 (0.73–1.73)

0.59

Grade

 I

Ref

Ref

 II

1.22 (1.03–1.43)

0.02*

 III/IV

0.43 (0.35–0.53)

< 0.01**

 Unknown

0.16 (0.06–0.42)

< 0.01**

LN Status

 Negative

Ref

Ref

 Positive

0.70 (0.58–0.86)

< 0.01**

 Unknown

0.21 (0.14–0.31)

< 0.01**

Tumor Size (mm)

 0.1–19

Ref

Ref

 20–39

1.69 (1.35–2.12)

< 0.01**

 > 40

0.88 (0.61–1.27)

0.48

 Unknown

0.92 (0.39–2.13)

0.84

Clinical Stage

 1

Ref

Ref

 2

0.80 (0.63–1.03)

0.08

 3 / 4

0.10 (0.06–0.17)

< 0.01**

MD Clinical Experience (Years)

 < 10

Ref

Ref

 10–19

0.89 (0.61–1.29)

0.53

 20–29

1.05 (0.71–1.57)

0.79

 > 29

1.07 (0.70–1.61)

0.76

MD Gender

 Female

Ref

Ref

 Male

0.98 (0.79–1.22)

0.88

Patient Volume

1.00 (0.99–1.01)

0.48

Average Patient Age

 < 65 Years

Ref

Ref

 > 65 Years

0.71 (0.49–1.03)

0.06

Surgical Specialty

 General Surgeon

Ref

Ref

 Surgical Oncologist

0.86 (0.70–1.06)

0.15

  1. * significant at the 0.05 level
  2. ** significant at the 0.01 level